A series of 5-alkoxy derivatives of 3, 4-dichloro-5-hydroxyfuran-2-(5H)-one (mucochloric
acid, MCA) were obtained and subsequently subjected to modification in the C-4 position of …

As one of the most lethal malignancies, lung cancer is considered to account for
approximately one-fifth of all malignant tumours-related deaths worldwide. This study reports …

Background: Compounds featuring furan nucleus exhibit diverse biological properties. Lots
of furan derivatives have been explored as pharmaceutical compounds. Hence it is of great …

In this work, the design, synthesis, and mechanistic studies of novel pyrazole‐based
benzofuran derivatives 1–8 as anticancer agents were discussed. Cytotoxic potency of the …

Dichloro‐2 (5H)‐furanone, which has been prepared efficiently from mucochloric acid, has
been transformed selectively into 4‐aryl‐3‐chloro‐2 (5H)‐furanones either by Suzuki‐or …

A series of 3, 4, 5-trisubstituted 2 (5H)-furanone derivatives was synthesized through one-
pot reaction of amines, aldehydes and diethyl acetylenedicarboxylate. Silica sulfuric acid …

New bis‐2 (5H)‐furanone derivatives containing a benzidine core were synthesized via a
one‐step transition‐metal‐free reaction of benzidine with 5‐substituted 3, 4‐dihalo‐2 (5H) …

In the present investigation, a collection of nineteen 3-(2-aryl-2-oxoethyl) isobenzofuran-1
(3H)-ones was synthesized and screened for their cytotoxic activity against a panel of three …

Benzofuran moiety is the main component of many biologically active natural and synthetic
heterocycles. These heterocycles have unique therapeutic potentials and are involved in …

A series of 3, 4-diaryl-2 (5H)-furanone derivatives were synthesized and evaluated for their
cytotoxicity in a small panel of cancer cell lines. Four out of 10 compounds in this series, for …