A genomic data archive from the Network for Pancreatic Organ donors with Diabetes

DJ Perry, MR Shapiro, SW Chamberlain, I Kusmartseva… - Scientific data, 2023 - nature.com
Abstract The Network for Pancreatic Organ donors with Diabetes (nPOD) is the largest
biorepository of human pancreata and associated immune organs from donors with type 1 …

Network for Pancreatic Organ Donors with Diabetes (nPOD): developing a tissue biobank for type 1 diabetes

M Campbell‐Thompson, C Wasserfall… - Diabetes/metabolism …, 2012 - Wiley Online Library
Abstract Background The Network for Pancreatic Organ Donors with Diabetes (nPOD) was
established to recover and characterize pancreata and related organs from cadaveric organ …

Organ donor specimens: What can they tell us about type 1 diabetes?

M Campbell‐Thompson - Pediatric diabetes, 2015 - Wiley Online Library
Type 1 diabetes (T1D) is a chronic disease resulting from the destruction of pancreatic beta
cells, due to a poorly understood combination of genetic, environmental, and immune …

New insight on human type 1 diabetes biology: nPOD and nPOD-transplantation

A Pugliese, F Vendrame, H Reijonen… - Current diabetes …, 2014 - Springer
Abstract The Juvenile Diabetes Research Foundation (JDRF) Network for Pancreatic Organ
Donors with Diabetes (JDRF nPOD) was established to obtain human pancreata and other …

Diabetes mellitus in living pancreas donors: use of integrated national registry and pharmacy claims data to characterize donation-related health outcomes

NN Lam, MA Schnitzler, DL Segev, GP Hess… - …, 2017 - journals.lww.com
Background Living donor pancreas transplant is a potential treatment for diabetic patients
with end-organ complications. Although early surgical risks of donation have been reported …

A run on the biobank: what have we learned about type 1 diabetes from the nPOD tissue repository?

JS Kaddis, A Pugliese, MA Atkinson - Current Opinion in …, 2015 - journals.lww.com
A run on the biobank: what have we learned about type 1 diab... : Current Opinion in
Endocrinology, Diabetes and Obesity A run on the biobank: what have we learned about type …

[HTML][HTML] Pancreas tissue slices from organ donors enable in situ analysis of type 1 diabetes pathogenesis

JK Panzer, H Hiller, CM Cohrs, J Almaça, SJ Enos… - JCI insight, 2020 - ncbi.nlm.nih.gov
In type 1 diabetes (T1D), autoimmune destruction of pancreatic β cells leads to insulin
deficiency and loss of glycemic control. However, knowledge about human pancreas …

Raising awareness: the need to promote allocation of pancreata from rare nondiabetic donors with pancreatic islet autoimmunity to type 1 diabetes research

GW Burke, AL Posgai, CH Wasserfall… - American Journal of …, 2017 - amjtransplant.org
We would like to engage the transplant community and ask for support of research about the
causes of type 1 diabetes (T1D). In this paper, we discuss the critical need to facilitate …

Global genomic and transcriptomic analysis of human pancreatic islets reveals novel genes influencing glucose metabolism

J Fadista, P Vikman, EO Laakso… - Proceedings of the …, 2014 - National Acad Sciences
Genetic variation can modulate gene expression, and thereby phenotypic variation and
susceptibility to complex diseases such as type 2 diabetes (T2D). Here we harnessed the …

Validation of a rapid type 1 diabetes autoantibody screening assay for community-based screening of organ donors to identify subjects at increased risk for the …

C Wasserfall, E Montgomery, L Yu… - Clinical & …, 2016 - academic.oup.com
Summary The Network for Pancreatic Organ donors with Diabetes (nPOD) programme was
developed in response to an unmet research need for human pancreatic tissue obtained …