3D polycaprolactone/gelatin-oriented electrospun scaffolds promote periodontal regeneration

X Xu, Y Zhou, K Zheng, X Li, L Li… - ACS Applied Materials & …, 2022 - ACS Publications
Periodontitis is a worldwide chronic inflammatory disease, where surgical treatment still
shows an uncertain prognosis. To break through the dilemma of periodontal treatment, we …

Bilayered construct for simultaneous regeneration of alveolar bone and periodontal ligament

MN Sundaram, S Sowmya, S Deepthi… - … Research Part B …, 2016 - Wiley Online Library
Periodontitis is an inflammatory disease that causes destruction of tooth‐supporting tissues
and if left untreated leads to tooth loss. Current treatments have shown limited potential for …

[HTML][HTML] Tissue-specific melt electrowritten polymeric scaffolds for coordinated regeneration of soft and hard periodontal tissues

A Daghrery, JA Ferreira, J Xu, N Golafshan, D Kaigler… - Bioactive Materials, 2023 - Elsevier
Periodontitis is a chronic inflammatory condition that often causes serious damage to tooth-
supporting tissues. The limited successful outcomes of clinically available approaches …

Periodontal ligament cellular structures engineered with electrospun poly(DL‐lactide‐co‐glycolide) nanofibrous membrane scaffolds

B Inanç, YE Arslan, S Seker, AE Elçin… - Journal of Biomedical …, 2009 - Wiley Online Library
Periodontal tissue engineering is expected to overcome the limitations associated with the
existing regenerative techniques for the treatment of periodontal defects involving alveolar …

[HTML][HTML] Synthesis of a novel electrospun polycaprolactone scaffold functionalized with ibuprofen for periodontal regeneration: An in vitro andin vivo study

F Batool, DN Morand, L Thomas, IM Bugueno… - Materials, 2018 - mdpi.com
Ibuprofen (IBU) has been shown to improve periodontal treatment outcomes. The aim of this
study was to develop a new anti-inflammatory scaffold by functionalizing an electrospun …

Incorporation of aligned PCL–PEG nanofibers into porous chitosan scaffolds improved the orientation of collagen fibers in regenerated periodontium

W Jiang, L Li, D Zhang, S Huang, Z Jing, Y Wu, Z Zhao… - Acta biomaterialia, 2015 - Elsevier
The periodontal ligament (PDL) is a group of highly aligned and organized connective tissue
fibers that intervenes between the root surface and the alveolar bone. The unique …

A highly ordered, nanostructured fluorinated CaP‐coated melt electrowritten scaffold for periodontal tissue regeneration

A Daghrery, JA Ferreira… - Advanced …, 2021 - Wiley Online Library
Periodontitis is a chronic inflammatory, bacteria‐triggered disorder affecting nearly half of
American adults. Although some level of tissue regeneration is realized, its low success in …

Hierarchically patterned triple-layered gelatin-based electrospun membrane functionalized by cell-specific extracellular matrix for periodontal regeneration

C Liang, G Wang, C Liang, M Li, Y Sun, W Tian, L Liao - Dental Materials, 2024 - Elsevier
Objectives Regenerating the periodontium poses a critical challenge in oral medicine. To
repair various periodontal defects, it is necessary to adopt a bio-scaffold that provides both …

[HTML][HTML] Medical-grade polycaprolactone scaffolds made by melt electrospinning writing for oral bone regeneration–a pilot study in vitro

A Fuchs, A Youssef, A Seher, G Hochleitner, PD Dalton… - BMC Oral Health, 2019 - Springer
Background The spectrum of indications for the use of membranes and scaffolds in the field
of oral and maxillofacial surgery includes, amongst others, guided bone regeneration (GBR) …

Composite graded melt electrowritten scaffolds for regeneration of the periodontal ligament-to-bone interface

N Golafshan, M Castilho, A Daghrery… - … applied materials & …, 2023 - ACS Publications
Periodontitis is a ubiquitous chronic inflammatory, bacteria-triggered oral disease affecting
the adult population. If left untreated, periodontitis can lead to severe tissue destruction …