Purpose In lung cancer, randomized trials assessing hyperfractionated or accelerated
radiotherapy seem to yield conflicting results regarding the effects on overall (OS) or …

BACKGROUND: Continuous hyperfractionated accelerated radiotherapy (CHART)
counteracts repopulation and may significantly improve outcome of patients with non-small …

Purpose The optimum dose and fractionation in radiation therapy of curative intent for non-
small cell lung cancer remains uncertain. We undertook a published data meta-analysis of …

Background Human tumour cells can proliferate rapidly, and giving radiotherapy in many
small fractions may reduce long-term normal-tissue morbidity. In response to these …

Purpose To identify survival and toxicity characteristics associated with radical-intent
hypofractionated radiotherapy for the treatment of stage III non–small-cell lung cancer …

Background and purpose A variety of radiotherapy fractionations are used as potentially
curative treatments for non-small cell lung cancer. In the UK, 55 Gy in 20 fractions over 4 …

Background and method: A randomised controlled trial in locally advanced non-small cell
lung cancer (NSCLC), compared CHART which employs 36 fractions of 1.5 Gy 3 times per …

Purpose To investigate whether the effect of hypofractionated thoracic radiotherapy (TRT) is
comparable to more standard fractionated radiotherapy (RT) in advanced non–small-cell …

PURPOSE: To review the published clinical data on non-small cell lung cancer treated with
radical radiotherapy to confirm a dose–response relationship as a basis for further dose …

A systematic review of radiation therapy trials in several tumour types was performed by The
Swedish Council of Technology Assessment in Health Care (SBU). The procedures for …