[HTML][HTML] A high-resolution transcriptomic and spatial atlas of cell types in the whole mouse brain

Z Yao, CTJ van Velthoven, M Kunst, M Zhang… - Nature, 2023 - nature.com
The mammalian brain consists of millions to billions of cells that are organized into many cell
types with specific spatial distribution patterns and structural and functional properties …

Molecularly defined and spatially resolved cell atlas of the whole mouse brain

M Zhang, X Pan, W Jung, AR Halpern, SW Eichhorn… - Nature, 2023 - nature.com
In mammalian brains, millions to billions of cells form complex interaction networks to enable
a wide range of functions. The enormous diversity and intricate organization of cells have …

Genome-wide atlas of gene expression in the adult mouse brain

ES Lein, MJ Hawrylycz, N Ao, M Ayres, A Bensinger… - Nature, 2007 - nature.com
Molecular approaches to understanding the functional circuitry of the nervous system
promise new insights into the relationship between genes, brain and behaviour. The cellular …

[HTML][HTML] Spatial atlas of the mouse central nervous system at molecular resolution

H Shi, Y He, Y Zhou, J Huang, K Maher, B Wang… - Nature, 2023 - nature.com
Spatially charting molecular cell types at single-cell resolution across the 3D volume is
critical for illustrating the molecular basis of brain anatomy and functions. Single-cell RNA …

The molecular cytoarchitecture of the adult mouse brain

J Langlieb, NS Sachdev, KS Balderrama, NM Nadaf… - Nature, 2023 - nature.com
The function of the mammalian brain relies upon the specification and spatial positioning of
diversely specialized cell types. Yet, the molecular identities of the cell types and their …

An anatomically comprehensive atlas of the adult human brain transcriptome

MJ Hawrylycz, ES Lein, AL Guillozet-Bongaarts… - Nature, 2012 - nature.com
Neuroanatomically precise, genome-wide maps of transcript distributions are critical
resources to complement genomic sequence data and to correlate functional and genetic …

A transcriptomic and epigenomic cell atlas of the mouse primary motor cortex

Z Yao, H Liu, F Xie, S Fischer, RS Adkins, AI Aldridge… - Nature, 2021 - nature.com
Single-cell transcriptomics can provide quantitative molecular signatures for large, unbiased
samples of the diverse cell types in the brain,–. With the proliferation of multi-omics datasets …

[HTML][HTML] Spatially resolved cell atlas of the mouse primary motor cortex by MERFISH

M Zhang, SW Eichhorn, B Zingg, Z Yao, K Cotter… - Nature, 2021 - nature.com
A mammalian brain is composed of numerous cell types organized in an intricate manner to
form functional neural circuits. Single-cell RNA sequencing allows systematic identification …

Transcriptional landscape of the prenatal human brain

JA Miller, SL Ding, SM Sunkin, KA Smith, L Ng… - Nature, 2014 - nature.com
The anatomical and functional architecture of the human brain is mainly determined by
prenatal transcriptional processes. We describe an anatomically comprehensive atlas of the …

Molecular features driving cellular complexity of human brain evolution

E Caglayan, F Ayhan, Y Liu, RM Vollmer, E Oh… - Nature, 2023 - nature.com
Human-specific genomic changes contribute to the unique functionalities of the human
brain,,,–. The cellular heterogeneity of the human brain, and the complex regulation of gene …