Host cell death is a critical component of innate immunity and often determines the
progression and outcome of infections. The opportunistic human pathogen Aspergillus …

The opportunistic human pathogenic fungus Aspergillus fumigatus produces at least two
types of melanin, namely pyomelanin and dihydroxynaphthalene (DHN) melanin …

The opportunistic human pathogenic fungus Aspergillus fumigatus (Af) causes the majority
of cases of invasive aspergillosis. Because Af enters the human body through inhalation of …

Aspergillus fumigatus is the most important air-borne fungal pathogen of humans. The
interaction of the pathogen with the host's immune system represents a key process to …

A major innate immune response to inhaled conidia of the opportunistic pathogen
Aspergillus fumigatus (Af) is the synthesis of pro-inflammatory cytokines, which include …

Invasive bronchopulmonary aspergillosis (IBPA) is a life-threatening disease in
immunocompromised patients. Although Aspergillus terreus is frequently found in the …

Aspergillus fumigatus is the most important air-borne pathogenic fungus of humans. Upon
inhalation of conidia, the fungus makes close contact with lung epithelial cells, which only …

Previously, we described the isolation of an Aspergillus fumigatus mutant producing non‐
pigmented conidia, as a result of a defective polyketide synthase gene, pksP (polyketide …

The conidial pigment of Aspergillus fumigatus contains 1, 8-dihydroxynaphthalene (DHN)-
like pentaketide melanin. It plays a major role in the protection of the fungus against immune …

The host's defense against invasive mold infections relies on diverse antimicrobial activities
of innate immune cells. However, studying these mechanisms in vitro is complicated by the …