A novel 14-amino acid peptide from yak alleviates kidney damage in the rat model of myocardial ischemia-reperfusion

D Qin, Z Hu, F Yang, T Xie, Q Wu, H Lu, W Guo, X Wu… - Food Bioscience, 2024 - Elsevier
Myocardial ischemia-reperfusion (MI/R) not only causes cardiac damage, but also causes
severe renal damage. T8 is the 8th peptide identified by peptiomics in digested yak milk …

A peptide from yak ameliorates hypoxia-induced kidney injury by inhibiting inflammation and apoptosis via Nrf2 pathway

F Yang, Z Chu, Q Wu, G Qu, Z He, J An, Y Tang, S Sun… - Food Bioscience, 2024 - Elsevier
Chronic kidney disease is a prevalent and severe significant complication of hypoxia. This
study found that peptide LVYPFPGPIPN could protect hypoxia-induced renal injury in the …

Preparation of antioxidant peptides from yak skin gelatin and their protective effect on myocardial ischemia reperfusion injury

C Jiang, A Meng, X Shi, Z Fu, Y Wang, J Zhou… - Food & Function, 2024 - pubs.rsc.org
We herein report a study on the antioxidant peptides that show potential in alleviating
myocardial ischemia reperfusion injury (MI/RI). Yak skin gelatin fraction Ac (YSG-Ac) …

Peptides isolated from yak milk residue exert antioxidant effects through Nrf2 signal pathway

F Yang, X He, T Chen, J Liu, Z Luo… - Oxidative Medicine …, 2021 - Wiley Online Library
Food‐derived bioactive peptides are considered as the important sources of natural
bioactive ingredients. Approximately 3094 peptides were identified by nESI‐LC–MS/MS in …

Bioactive peptides attenuate cardiac apoptosis in spontaneously hypertensive rat hearts through activation of autophagy and mitochondrial biogenesis pathway

WT Lin, S Nithiyanantham, DJY Hsieh… - Environmental …, 2020 - Wiley Online Library
Alcalase potato protein hydrolysate (APPH) might have a very important role in therapeutic
effects. This study aims to examine the beneficial effects of bioactive peptides (DIKTNKPVIF …

Network pharmacology and experimental validation to investigate the mechanism of Nao-Ling-Su capsule in the treatment of ischemia/reperfusion-induced acute …

Y Lin, L Xu, H Lin, W Cui, Y Jiao, B Wang, H Li… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance Nao-Ling-Su Capsule (NLSC) is a traditional
prescription, which is composed of fifteen herbs such as epimedium, Polygala tenuifolia, and …

Protective Effects of Rice Peptide Oryza Peptide-P60 against Oxidative Injury through Activation of Nrf2 Signaling Pathway In Vitro and In Vivo

C Moritani, K Kawakami, H Shimoda, T Hatanaka… - Acs Omega, 2020 - ACS Publications
We previously showed that commercially available rice peptide Oryza Peptide-P60 (OP60)
increased the intracellular glutathione levels. This study aimed to evaluate the antioxidant …

Peptide T8 isolated from yak milk residue ameliorates H2O2-induced oxidative stress through Nrf2 signaling pathway in HUVEC cells

D Qin, F Yang, Z Hu, J Liu, Q Wu, Y Luo, L Yang, S Han… - Food Bioscience, 2021 - Elsevier
This study was aimed to explore the anti-oxidative effect of active peptide (T8) isolated from
yak milk residue on H 2 O 2-induced damage in HUVEC cells. The results showed that …

[HTML][HTML] An active peptide from yak inhibits hypoxia-induced lung injury via suppressing VEGF/MAPK/inflammatory signaling

F Yang, Z He, Z Chu, W Li, G Qu, H Lu, Y Tang, S Sun… - Redox Biology, 2024 - Elsevier
Pulmonary vascular remodeling and inflammation play an important role in the hypoxic-
induced lung diseases. Our previous investigations showed that peptide from yak milk …

Bioactive peptide F2d isolated from rice residue exerts antioxidant effects via Nrf2 signaling pathway

J Liu, Q Wu, T Yang, F Yang, T Guo… - Oxidative Medicine …, 2021 - Wiley Online Library
Studies have shown that the peroxidation caused by oxygen free radicals is an important
reason of vascular endothelial dysfunction and multiple diseases. In this study, active …