Exploring the impact of hydrogen sulfide on hematologic malignancies: A review

S Lou, ZL Jiang, YW Zhu, RY Zhang, Y Wang, T Chu… - Cellular …, 2024 - Elsevier
Hydrogen sulfide (H 2 S) is one of the three most crucial gaseous messengers in the body.
The discovery of H 2 S donors, coupled with its endogenous synthesis capability, has …

[HTML][HTML] Hydrogen sulfide biology and its role in cancer

S Khattak, MA Rauf, NH Khan, QQ Zhang, HJ Chen… - Molecules, 2022 - mdpi.com
Hydrogen sulfide (H2S) is an endogenous biologically active gas produced in mammalian
tissues. It plays a very critical role in many pathophysiological processes in the body. It can …

[HTML][HTML] Molecular functions of hydrogen sulfide in cancer

RE Shackelford, IZ Mohammad, AT Meram, D Kim… - Pathophysiology, 2021 - mdpi.com
Hydrogen sulfide (H2S) is a gasotransmitter that exerts a multitude of functions in both
physiologic and pathophysiologic processes. H2S-synthesizing enzymes are increased in a …

[HTML][HTML] Role of hydrogen sulfide donors in cancer development and progression

EE Ngowi, A Afzal, M Sarfraz, S Khattak… - … Journal of Biological …, 2021 - ncbi.nlm.nih.gov
In recent years, a vast number of potential cancer therapeutic targets have emerged.
However, developing efficient and effective drugs for the targets is of major concern …

[HTML][HTML] The hidden role of hydrogen sulfide metabolism in cancer

RH Wang, YH Chu, KT Lin - International Journal of Molecular Sciences, 2021 - mdpi.com
Hydrogen Sulfide (H2S), an endogenously produced gasotransmitter, is involved in various
important physiological and disease conditions, including vasodilation, stimulation of …

Hydrogen sulfide signaling in the tumor microenvironment: implications in cancer progression and therapy

JA Machado-Neto, ARA Cerqueira… - Antioxidants & Redox …, 2024 - liebertpub.com
Significance: Cancer is a complex and heterotypic structure with a spatial organization that
contributes to challenges in therapeutics. Enzymes associated with producing the …

Recent advances in the role of endogenous hydrogen sulphide in cancer cells

HJ Chen, K Li, YZ Qin, JJ Zhou, T Li, L Qian… - Cell …, 2023 - Wiley Online Library
Hydrogen sulphide (H2S) is a gaseous neurotransmitter that can be self‐synthesized by
living organisms. With the deepening of research, the pathophysiological mechanisms of …

[Corrigendum] Exogenous hydrogen sulfide exerts proliferation, anti-apoptosis, migration effects and accelerates cell cycle progression in multiple myeloma cells via …

D Zheng, Z Chen, J Chen, X Zhuang… - oncology …, 2021 - spandidos-publications.com
Dong Zheng, ZIang chen, JIngfu chen, XIaomIn Zhuang, JIanqIang feng and Juan lI oncol
rep 36: 1909-1916, 2016; DoI: 10.3892/or. 2016.5014 following the publication of this article …

[HTML][HTML] Endogenously produced hydrogen sulfide supports tumor cell growth and proliferation

C Szabo, MR Hellmich - Cell Cycle, 2013 - Taylor & Francis
2916 Cell Cycle Volume 12 issue 18 molecular relationship between these pathways
remains to be delineated, it is conceivable that the energetic and signaling responses act in …

Hydrogen sulfide metabolism and signaling in the tumor microenvironment

A Giuffrè, CS Tomé, DGF Fernandes, K Zuhra… - … : The Main Driver of …, 2020 - Springer
Abstract Hydrogen sulfide (H 2 S), while historically perceived merely as a toxicant, has
progressively emerged as a key regulator of numerous processes in mammalian physiology …