Regulation of AMPA receptor trafficking and synaptic plasticity

V Anggono, RL Huganir - Current opinion in neurobiology, 2012 - Elsevier
AMPA receptors (AMPARs) mediate the majority of fast excitatory synaptic transmission in
the brain. Dynamic changes in neuronal synaptic efficacy, termed synaptic plasticity, are …

The cell biology of synaptic plasticity: AMPA receptor trafficking

JD Shepherd, RL Huganir - Annu. Rev. Cell Dev. Biol., 2007 - annualreviews.org
The cellular processes that govern neuronal function are highly complex, with many basic
cell biological pathways uniquely adapted to perform the elaborate information processing …

Posttranslational regulation of AMPA receptor trafficking and function

W Lu, KW Roche - Current opinion in neurobiology, 2012 - Elsevier
In the mammalian central nervous system, the majority of fast excitatory synaptic
transmission is mediated by glutamate acting on AMPA-type ionotropic glutamate receptors …

Synaptic AMPA receptor composition in development, plasticity and disease

JM Henley, KA Wilkinson - Nature Reviews Neuroscience, 2016 - nature.com
AMPA receptors (AMPARs) are assemblies of four core subunits, GluA1–4, that mediate
most fast excitatory neurotransmission. The component subunits determine the functional …

Routes, destinations and delays: recent advances in AMPA receptor trafficking

JM Henley, EA Barker, OO Glebov - Trends in neurosciences, 2011 - cell.com
Postsynaptic AMPA-type glutamate receptors (AMPARs) mediate most fast excitatory
synaptic transmission and are crucial for many aspects of brain function, including learning …

[HTML][HTML] Reinsertion or degradation of AMPA receptors determined by activity-dependent endocytic sorting

MD Ehlers - Neuron, 2000 - cell.com
Both acute and chronic changes in AMPA receptor (AMPAR) localization are critical for
synaptic formation, maturation, and plasticity. Here I report that AMPARs are differentially …

[HTML][HTML] AMPA receptors and their minions: auxiliary proteins in AMPA receptor trafficking

D Bissen, F Foss, A Acker-Palmer - Cellular and Molecular Life Sciences, 2019 - Springer
To correctly transfer information, neuronal networks need to continuously adjust their
synaptic strength to extrinsic stimuli. This ability, termed synaptic plasticity, is at the heart of …

[HTML][HTML] The regulation of AMPA receptor endocytosis by dynamic protein-protein interactions

JG Hanley - Frontiers in cellular neuroscience, 2018 - frontiersin.org
The precise regulation of AMPA receptor (AMPAR) trafficking in neurons is crucial for
excitatory neurotransmission, synaptic plasticity and the consequent formation and …

Regulatory mechanisms of AMPA receptors in synaptic plasticity

VA Derkach, MC Oh, ES Guire… - Nature Reviews …, 2007 - nature.com
Activity-dependent changes in the strength of excitatory synapses are a cellular mechanism
for the plasticity of neuronal networks that is widely recognized to underlie cognitive …

[HTML][HTML] AMPA-receptor specific biogenesis complexes control synaptic transmission and intellectual ability

A Brechet, R Buchert, J Schwenk, S Boudkkazi… - Nature …, 2017 - nature.com
AMPA-type glutamate receptors (AMPARs), key elements in excitatory neurotransmission in
the brain, are macromolecular complexes whose properties and cellular functions are …