Biocompatibility of hydrogel-based scaffolds for tissue engineering applications

S Naahidi, M Jafari, M Logan, Y Wang, Y Yuan… - Biotechnology …, 2017 - Elsevier
Recently, understanding of the extracellular matrix (ECM) has expanded rapidly due to the
accessibility of cellular and molecular techniques and the growing potential and value for …

The engineering and application of extracellular matrix hydrogels: a review

Y Zhang, Y Xu, J Gao - Biomaterials science, 2023 - pubs.rsc.org
This review provides an overview of the engineering and application of extracellular matrix
(ECM) hydrogels. ECM hydrogels are attractive materials for tissue engineering and …

Engineering biosynthetic cell encapsulation systems

JJ Roberts, PJ Martens - Biosynthetic polymers for medical applications, 2016 - Elsevier
Hydrogels have widespread use for cell encapsulation because of their ability to be
processed under relatively mild conditions and to mimic native tissue hydration, mechanics …

Hydrogels for tissue engineering: scaffold design variables and applications

JL Drury, DJ Mooney - Biomaterials, 2003 - Elsevier
Polymer scaffolds have many different functions in the field of tissue engineering. They are
applied as space filling agents, as delivery vehicles for bioactive molecules, and as three …

Design properties of hydrogel tissue-engineering scaffolds

J Zhu, RE Marchant - Expert review of medical devices, 2011 - Taylor & Francis
This article summarizes the recent progress in the design and synthesis of hydrogels as
tissue-engineering scaffolds. Hydrogels are attractive scaffolding materials owing to their …

Engineering hydrogels as extracellular matrix mimics

H Geckil, F Xu, X Zhang, SJ Moon, U Demirci - Nanomedicine, 2010 - Taylor & Francis
Extracellular matrix (ECM) is a complex cellular environment consisting of proteins,
proteoglycans, and other soluble molecules. ECM provides structural support to mammalian …

Natural polymer-based hydrogels as scaffolds for tissue engineering

MR Singh, S Patel, D Singh - Nanobiomaterials in soft tissue engineering, 2016 - Elsevier
Hydrogels have increased attention in drug-delivery systems and other areas of biomedical
engineering. Hydrogels are a remarkable strategy to develop scaffolds for tissue …

Synthetic mimics of the extracellular matrix: how simple is complex enough?

KA Kyburz, KS Anseth - Annals of biomedical engineering, 2015 - Springer
Cells reside in a complex and dynamic extracellular matrix where they interact with a myriad
of biophysical and biochemical cues that direct their function and regulate tissue …

Hydrogels in regenerative medicine

BV Slaughter, SS Khurshid, OZ Fisher… - Advanced …, 2009 - Wiley Online Library
Hydrogels, due to their unique biocompatibility, flexible methods of synthesis, range of
constituents, and desirable physical characteristics, have been the material of choice for …

New insights of scaffolds based on hydrogels in tissue engineering

DM Radulescu, IA Neacsu, AM Grumezescu… - Polymers, 2022 - mdpi.com
In recent years, biomaterials development and characterization for new applications in
regenerative medicine or controlled release represent one of the biggest challenges. Tissue …