Synchronous neurotransmitter release is triggered by Ca2+ binding to the synaptic vesicle
protein Synaptotagmin 1, while asynchronous fusion and short-term facilitation is …

Ca2+ influx into presynaptic nerve terminals activates synaptic vesicle exocytosis by
triggering fast synchronous fusion and a slower asynchronous release pathway. In addition …

Synaptic vesicle fusion at many synapses has been kinetically separated into two distinct
Ca2+-dependent temporal components consisting of a rapid synchronous phase followed …

Synaptotagmin (syt) 7 is one of three syt isoforms found in all metazoans; it is ubiquitously
expressed, yet its function in neurons remains obscure. Here, we resolved Ca2+-dependent …

Synaptotagmin 1 (Syt1) is a synaptic vesicle integral membrane protein that regulates
neurotransmitter release by activating fast synchronous fusion and suppressing slower …

The Synaptotagmin (SYT) family of proteins play key roles in regulating membrane
trafficking at neuronal synapses. Using both Ca 2+-dependent and Ca 2+-independent …

The synaptotagmin family of vesicle proteins is believed to mediate calcium-dependent
regulation of membrane trafficking. Detailed biochemical and in vivo studies of the most …

Synaptotagmin 1 (Syt1) is a Ca2+ sensor for SNARE-mediated, Ca2+-triggered synaptic
vesicle fusion in neurons. It is composed of luminal, transmembrane, linker, and two Ca2+ …

Synaptotagmin 1 (Syt1) synchronizes neurotransmitter release to action potentials (APs)
acting as the fast Ca2+ release sensor and as the inhibitor (clamp) of spontaneous and …

Ca2+ influx into synaptic compartments during activity is a key mediator of neuronal
plasticity. Although the role of presynaptic Ca2+ in triggering vesicle fusion though the Ca2+ …