[HTML][HTML] The conserved molecular machinery in DNA mismatch repair enzyme structures
FS Groothuizen, TK Sixma - DNA repair, 2016 - Elsevier
The machinery of DNA mismatch repair enzymes is highly conserved in evolution. The
process is initiated by recognition of a DNA mismatch, and validated by ATP and the …
process is initiated by recognition of a DNA mismatch, and validated by ATP and the …
DNA mismatch repair
TA Kunkel, DA Erie - Annu. Rev. Biochem., 2005 - annualreviews.org
▪ Abstract DNA mismatch repair (MMR) is an evolutionarily conserved process that corrects
mismatches generated during DNA replication and escape proofreading. MMR proteins also …
mismatches generated during DNA replication and escape proofreading. MMR proteins also …
DNA mismatch repair system: Classical and fresh roles
SH Jun, TG Kim, C Ban - The FEBS journal, 2006 - Wiley Online Library
The molecular mechanisms of the DNA mismatch repair (MMR) system have been
uncovered over the last decade, especially in prokaryotes. The results obtained for …
uncovered over the last decade, especially in prokaryotes. The results obtained for …
New insights into the mechanism of DNA mismatch repair
GX Reyes, TT Schmidt, RD Kolodner, H Hombauer - Chromosoma, 2015 - Springer
The genome of all organisms is constantly being challenged by endogenous and
exogenous sources of DNA damage. Errors like base: base mismatches or small insertions …
exogenous sources of DNA damage. Errors like base: base mismatches or small insertions …
Mismatch repair proteins: key regulators of genetic recombination
Mismatch repair (MMR) systems are central to maintaining genome stability in prokaryotes
and eukaryotes. MMR proteins play a fundamental role in avoiding mutations, primarily by …
and eukaryotes. MMR proteins play a fundamental role in avoiding mutations, primarily by …
Coupling distant sites in DNA during DNA mismatch repair
RD Kolodner, ML Mendillo… - Proceedings of the …, 2007 - National Acad Sciences
How can the activities of differ-ent proteins that act at two distant sites on DNA be coupled?
In cis mechanisms, an intact DNA helix is required so that the protein molecules can slide …
In cis mechanisms, an intact DNA helix is required so that the protein molecules can slide …
DNA mismatch repair in eukaryotes and bacteria
K Fukui - Journal of nucleic acids, 2010 - Wiley Online Library
DNA mismatch repair (MMR) corrects mismatched base pairs mainly caused by DNA
replication errors. The fundamental mechanisms and proteins involved in the early reactions …
replication errors. The fundamental mechanisms and proteins involved in the early reactions …
Postreplicative mismatch repair
J Jiricny - Cold Spring Harbor perspectives in biology, 2013 - cshperspectives.cshlp.org
The mismatch repair (MMR) system detects non-Watson–Crick base pairs and strand
misalignments arising during DNA replication and mediates their removal by catalyzing …
misalignments arising during DNA replication and mediates their removal by catalyzing …
Eukaryotic DNA mismatch repair
RD Kolodner, GT Marsischky - Current opinion in genetics & development, 1999 - Elsevier
Eukaryotic mismatch repair (MMR) has been shown to require two different heterodimeric
complexes of MutS-related proteins: MSH2–MSH3 and MSH2–MSH6. These two complexes …
complexes of MutS-related proteins: MSH2–MSH3 and MSH2–MSH6. These two complexes …
The unstructured linker arms of Mlh1–Pms1 are important for interactions with DNA during mismatch repair
DNA mismatch repair (MMR) models have proposed that MSH (MutS homolog) proteins
identify DNA polymerase errors while interacting with the DNA replication fork. MLH (MutL …
identify DNA polymerase errors while interacting with the DNA replication fork. MLH (MutL …