Background: Computational fluid dynamics allow virtual evaluation of coronary physiology
and shear stress (SS). Most studies hitherto assumed the vessel as a single conduit without …

Image-based computational models for quantifying hemodynamic indices in stented
coronary arteries often employ biplane angiography and intravascular ultrasound for 3D …

Genesis of atherosclerotic lesions in the human arterial system is critically influenced by the
fluid mechanics. Applying computational fluid dynamic tools based on accurate coronary …

Abstract Background Geometrically-correct 3D OCT is a new imaging modality with the
potential to investigate the association of local hemodynamic microenvironment with OCT …

Background Clinical studies suggest that local wall shear stress (WSS) patterns modulate
the site and the progression of atherosclerotic lesions. Computational fluid dynamics (CFD) …

AIMS: Wall shear stress (WSS) may induce local remodeling of the vascular wall and the
WSS pattern in turn depends on vascular geometry. We aimed to elucidate the impact of …

Background and aims Low and high endothelial shear stress (ESS) is associated with
coronary atherosclerosis progression and high-risk plaque features. Coronary ESS is …

Aims: To develop a methodology that permits accurate 3-dimensional (3D) reconstruction
from FD-OCT and angiographic data enabling reliable evaluation of the ESS distribution …

Endothelial shear stress (ESS) identifies coronary plaques at high risk for progression
and/or rupture leading to a future acute coronary syndrome. In this study an optimized …

Local hemodynamic parameters, such as wall shear stress (WSS), oscillatory shear index
and relative resident time (RRT), have been linked to coronary plaque initiation and …