Islet culture before clinical transplantation has been adopted by various centers, but its effect
on the survival and function of islets relative to the culture conditions and media needs …

The ability to maintain isolated human islet preparations in tissue culture has recently been
adopted by most islet transplant centers, and improves the safety as well as the practicality …

Background. The original Edmonton protocol used fresh islets, but for obvious logistic
advantages most transplant centers have implemented pretransplant culture in human …

Background. Although culturing islets before transplantation provides flexibility for
evaluation of isolated islets and pretreatment of patients, it is well-known that isolated islets …

For clinical islet transplantation, isolated islets deteriorate rapidly in culture, although
culturing islets prior to transplantation provides flexibility for evaluation of isolated islets and …

Pancreatic islet transplantation has received widespread attention as a promising treatment
for type 1 diabetes. However, islets for transplantation are subject to damage from a number …

Culturing islets can add great flexibility to a clinical islet transplant program. However, a
reduction in the islet mass has been frequently observed during culture and its degree …

INTRODUCTION: It has recently been reported that the outcomes of islet transplantation with
short periods of culture are comparable with those of freshly isolated islets. To clarify the …

Although islet culture prior to transplantation provides flexibility for the evaluation of isolated
islets and the pretreatment of patients, it is well known that isolated islets deteriorate rapidly …

Clinical islet transplantation invariably requires more than one donor per recipient. Delay
between transplants could be reduced if islets were stored and transported between centers …