Asthma therapy and its effect on airway remodelling

R Berair, CE Brightling - Drugs, 2014 - Springer
Asthma remains a major health problem with significant morbidity, mortality and economic
costs. In asthma, airway remodelling, which refers to all the microscopic structural changes …

Airway remodelling in asthma: current understanding and implications for future therapies

MLK Tang, JW Wilson, AG Stewart, SG Royce - Pharmacology & …, 2006 - Elsevier
Airway remodelling refers to the structural changes that occur in the airway wall in asthma.
These include epithelial hyperplasia and metaplasia, subepithelial fibrosis, muscle cell …

Airway remodelling in asthma

R Beasley, C Page… - Clinical & Experimental …, 2002 - Wiley Online Library
Airway remodelling is a relatively new concept in asthma research. It can be defined as the
'structural changes in the airways that may affect their functional properties'. The structural …

What effect does asthma treatment have on airway remodeling? Current perspectives

SR Durrani, RK Viswanathan, WW Busse - Journal of Allergy and Clinical …, 2011 - Elsevier
Airway remodeling, or structural changes of the airway wall arising from injury and repair,
plays an important role in the pathophysiology of asthma. Remodeling is characterized as …

Airway remodeling in asthma

AM Vignola, F Mirabella, G Costanzo, R Di Giorgi… - Chest, 2003 - Elsevier
Chronic inflammation and remodeling may follow acute inflammation or may begin
insidiously as a low-grade smoldering response, especially in the case of immune reactions …

Airway remodeling: a potential therapeutic target in asthma

WX Zhang, CC Li - World Journal of Pediatrics, 2011 - Springer
Background Apart from airway inflammation, airway remodeling is one of the main
pathological features of asthma. However, it remains unclear when airway remodeling starts …

Airway remodeling in asthma

PG Woodruff, JV Fahy - Seminars in respiratory and critical care …, 2002 - thieme-connect.com
Airway remodeling is a summary term for the pathological changes that occur in airway
structure in allergic or suppurative airway diseases. Characteristic changes of airway …

Airway remodeling in asthma: update on mechanisms and therapeutic approaches

LP Boulet - Current opinion in pulmonary medicine, 2018 - journals.lww.com
Airway remodeling in asthma: update on mechanisms and therap... : Current Opinion in
Pulmonary Medicine Airway remodeling in asthma: update on mechanisms and therapeutic …

Airway remodelling in asthma: from benchside to clinical practice

C Bergeron, MK Tulic, Q Hamid - Canadian respiratory journal, 2010 - Wiley Online Library
Airway remodelling refers to the structural changes that occur in both large and small
airways relevant to miscellaneous diseases including asthma. In asthma, airway structural …

Pharmacotherapy and airway remodelling in asthma?

PA Beckett, PH Howarth - Thorax, 2003 - thorax.bmj.com
Over the last few decades attention has largely focused on airway inflammation in asthma,
but more recently it has been appreciated that there are important structural airway changes …