Diabetic kidney disease (DKD) is a major cause of end-stage kidney disease, and it is
crucial to understand the pathophysiology of DKD. The control of blood glucose levels by …

Chronic kidney disease is generally progressive and currently has no reliable treatment to
reverse a decline in kidney function or to slow the progression of the disease. Diabetic …

Diabetes mellitus (DM) is one of the most debilitating chronic diseases worldwide, with
increased prevalence and incidence. In addition to its macrovascular damage, through its …

Oxidative stress and inflammation are mediators in the development and progression of
chronic kidney disease (CKD) and its complications, and they are inseparably linked as …

Drugs targeting the renin‐angiotensin‐aldosterone system (RAAS) are the mainstay of
therapy to retard the progression of proteinuric chronic kidney disease (CKD) such as …

Diabetic kidney disease (DKD) has become the leading cause of end-stage renal disease
(ESRD), and the prevalence of DKD has increased worldwide during recent years. DKD is …

Accumulating research suggests that oxidative stress is a significant contributor to the
pathogenesis of diabetic nephropathy. The normal kidney generates a substantial amount of …

Diabetic nephropathy (DN), a progressive kidney disease afflicts more than 20 and up to
40% of the diabetic population and it is characterized by persistent microalbuminuria …

Diabetes mellitus (DM) belongs to the category of socially significant diseases with epidemic
rates of increases in prevalence. Diabetic nephropathy (DN) is a specific kind of kidney …

Excessive production of reactive oxygen species is an important mechanism underlying the
pathogenesis of diabetes associated macrovascular and microvascular complications …