Sensory epithelia of the inner ear contain two major cell types: hair cells and supporting
cells. It has been clear for a long time that hair cells play critical roles in mechanoreception …

The sensory epithelia of the inner ear contain mechanosensory hair cells and non-sensory
supporting cells. Both classes of cell are heterogeneous, with phenotypes varying both …

The mammalian inner ear largely lacks the capacity to regenerate hair cells, the sensory
cells required for hearing and balance. Recent studies in both lower vertebrates and …

In vertebrates, perception of sound, motion, and balance is mediated through
mechanosensory hair cells located within the inner ear. In mammals, hair cells are only …

Many studies that aim to investigate the underlying mechanisms of hearing loss or balance
disorders focus on the hair cells and spiral ganglion neurons of the inner ear. Fewer studies …

The inner ear sensory epithelia contain mechanosensitive hair cells and supporting cells.
Both cell types arise from SOX2-expressing prosensory cells, but the mechanisms …

Sensory hair cells of the inner ear are responsible for translating auditory or vestibular
stimuli into electrical energy that can be perceived by the nervous system. Although hair …

Cochlear hair cells are mechanoreceptors of the auditory system and cannot spontaneously
regenerate in adult mammals; thus hearing loss due to hair cell damage is permanent. In …

Advances in hair cell regeneration are progressing at a rapid rate. This review will highlight
and critique recent attempts to understand some of the cellular and molecular mechanisms …

Sensory hair cell loss is a major contributor to disabling hearing and balance deficits that
affect> 250 million people worldwide. Sound exposures, infections, drug toxicity, genetic …