Garlic (Allium sativum)-derived SEVs inhibit cancer cell proliferation and induce caspase mediated apoptosis

İ Özkan, P Koçak, M Yıldırım, N Ünsal, H Yılmaz… - Scientific reports, 2021 - nature.com
As a key component of the cell-to-cell communication, small extracellular vesicles (SEVs)
released from various sources are known to be affecting the physiological conditions of the …

Engineering Exosome-Like Nanovesicles Derived from Asparagus cochinchinensis Can Inhibit the Proliferation of Hepatocellular Carcinoma Cells with Better Safety …

L Zhang, F He, L Gao, M Cong, J Sun, J Xu… - International Journal …, 2021 - Taylor & Francis
Background Exosomes are a type of membrane vesicles secreted by living cells. Recent
studies suggest exosome-like nanovesicles (ELNVs) from fruits and vegetables are involved …

Garlic constituent diallyl trisulfide induced apoptosis in MCF7 human breast cancer cells

A Malki, M El-Saadani, AS Sultan - Cancer biology & therapy, 2009 - Taylor & Francis
Identification of agents that are nontoxic but can delay onset and/or progression of breast
cancer, which is the main leading cause of cancer-related deaths among women, is highly …

Bitter melon derived extracellular vesicles enhance the therapeutic effects and reduce the drug resistance of 5-fluorouracil on oral squamous cell carcinoma

M Yang, Q Luo, X Chen, F Chen - Journal of nanobiotechnology, 2021 - Springer
Background Plant-derived extracellular vesicles (PDEVs) have been exploited for cancer
treatment with several benefits. Bitter melon is cultivated as a vegetable and folk medicine …

Selenium nanoparticles as a carrier of 5-fluorouracil to achieve anticancer synergism

W Liu, X Li, YS Wong, W Zheng, Y Zhang, W Cao… - ACS …, 2012 - ACS Publications
A simple method for preparing 5-fluorouracil surface-functionalized selenium nanoparticles
(5FU-SeNPs) with enhanced anticancer activity has been demonstrated in the present study …

Antiproliferative and Apoptotic Effects of Sesbania grandiflora Leaves in Human Cancer Cells

S Pajaniradje, K Mohankumar… - BioMed research …, 2014 - Wiley Online Library
Natural phytochemicals and their derivatives are good drug candidates for anticancer
therapeutic approaches against multiple targets. We report here the initial findings from our …

Diallyl trisulfide induces apoptosis in human primary colorectal cancer cells

CS Yu, AC Huang, KC Lai, YP Huang… - Oncology …, 2012 - spandidos-publications.com
Colorectal cancer (CRC) is one of the most prevalent types of cancer worldwide and a
common cause of morbidity and mortality in humans. The garlic-derived organosulfur …

Garlic-derived organosulfur compound exerts antitumor efficacy via activation of MAPK pathway and modulation of cytokines in SGC-7901 tumor-bearing mice

X Jiang, X Zhu, W Huang, H Xu, Z Zhao, S Li… - International …, 2017 - Elsevier
Diallyl trisulfide (DATS), a natural agent derived from garlic, has been tested for its
antigastric cancer activities in various preliminary studies. However, more systematic …

Diallyl disulfide causes caspase-dependent apoptosis in human cancer cells through a Bax-triggered mitochondrial pathway

NS Nagaraj, KR Anilakumar, OV Singh - The Journal of nutritional …, 2010 - Elsevier
Diallyl disulfide (DADS), an important component of garlic (Allium sativum) derivative, has
been demonstrated to exert a potential molecular target against human cancers. We …

Diallyl trisulfide induces Bcl-2 and caspase-3-dependent apoptosis via downregulation of Akt phosphorylation in human T24 bladder cancer cells

YB Wang, J Qin, XY Zheng, Y Bai, K Yang, LP Xie - Phytomedicine, 2010 - Elsevier
It is well known that the garlic-derived organosulfur compounds (OSCs) are effective to
inhibit a variety of human cancers such as prostate, breast, colon, skin, lung, and bladder …