An imbalance between reactive oxygen species and antioxidant reserve, referred to as
oxidative stress, results in the altered structure and function of proteins, lipids and DNA …

In recent years, diabetes and its associated complications have come to represent a major
public health concern. It is a complex disease characterized by multiple metabolic …

The notion of oxidative stress has changed over the past decades from the idea of being a
phenomenon involved exclusively with oxidative damage to a more contemporary concept …

Oxidative stress is a mechanism with a central role in the pathogenesis of atherosclerosis,
cancer, and other chronic diseases. It also plays a major role in the aging process. Ischemic …

A multitude of studies in experimental animals, together with clinical data, provide evidence
that increased production of ROS (reactive oxygen species) are involved in the development …

Oxidative stress and cardiovascular disease: new insights Page 1 Address for correspondence:
Prof. Francesco Violi, I Clinica Medica, Viale del Policlinico 155, Roma, 00161, Italy, tel …

Understanding of the pathophysiology of atherosclerosis can provide new strategies for the
prevention and treatment of patients with this common disease. Clinical, epidemiologic, and …

During the past few decades, there have been numerous studies related to free radical
chemistry. Free radicals including reactive oxygen species (ROS) and reactive nitrogen …

Type 2 diabetes is a worldwide increasing disease resulting from the interaction between a
subject's genetic makeup and lifestyle. In genetically predisposed subjects, the combination …

Cardiovascular disease is the most common cause of mortality in the Western world and
accounts for up to a third of all deaths worldwide. Cardiovascular disease is multifactorial …