Circulating tumour DNA as biomarker for colorectal liver metastases: a systematic review and meta-analysis

L Wullaert, JM van Rees, JWM Martens, HMW Verheul… - Cells, 2023 - mdpi.com
Circulating tumour DNA (ctDNA) is a potential biomarker that could contribute to more
judicious patient selection for personalised treatment. This review and meta-analysis gives …

Postoperative circulating tumour DNA is associated with pathologic response and recurrence-free survival after resection of colorectal cancer liver metastases

K Bolhuis, I van't Erve, C Mijnals… - …, 2021 - thelancet.com
Background Recurrence rates after resection of colorectal cancer liver metastases (CRLM)
are high and correlate with worse survival. Postoperative circulating tumour DNA (ctDNA) is …

Circulating tumor DNA dynamics and recurrence risk in patients undergoing curative intent resection of colorectal cancer liver metastases: A prospective cohort study

J Tie, Y Wang, J Cohen, L Li, W Hong, M Christie… - PLoS …, 2021 - journals.plos.org
Background In patients with resectable colorectal liver metastases (CRLM), the role of pre-
and postoperative systemic therapy continues to be debated. Previous studies have shown …

Circulating tumour DNA and its clinical utility in predicting treatment response or survival in patients with metastatic colorectal cancer: a systematic review and meta …

LB Callesen, J Hamfjord, AK Boysen… - British Journal of …, 2022 - nature.com
Background We investigate the current knowledge on circulating tumour DNA (ctDNA) and
its clinical utility in predicting outcomes in patients with metastatic colorectal cancer (mCRC) …

Circulating tumor DNA for prognosis assessment and postoperative management after curative‐intent resection of colorectal liver metastases

T Reinert, LMS Petersen, TV Henriksen… - … journal of cancer, 2022 - Wiley Online Library
The recurrence rate of colorectal liver metastases (CRLM) patients treated with curative
intent is above 50%. Standard of care surveillance includes intensive computed …

Serial circulating tumor DNA (ctDNA) and recurrence risk in patients (pts) with resectable colorectal liver metastasis (CLM).

J Tie, Y Wang, S Springer, I Kinde, HL Wong… - 2016 - ascopubs.org
e15131 Background: In pts with metastatic colorectal cancer (mCRC), the resection of
isolated CLM is potentially curative. Previous studies have shown that ctDNA can be …

Circulating tumor DNA as a marker of minimal residual disease after radical resection of colorectal liver metastases

F Marmorino, M Prisciandaro, M Giordano… - JCO precision …, 2022 - ascopubs.org
PURPOSE Prognostic tools to estimate the risk of relapse for patients with liver-limited
metastatic colorectal cancer (LL-mCRC) undergoing resection with curative intent are …

Recurrence prediction by circulating tumor DNA in the patient with colorectal liver metastases after hepatectomy: a prospective biomarker study

W Liu, KM Jin, MH Zhang, Q Bao, M Liu, D Xu… - Annals of Surgical …, 2023 - Springer
Background The recurrence rate after hepatic resection of colorectal liver metastases
(CRLM) remains high. This study aimed to investigate postoperative circulating tumor DNA …

Perioperative circulating tumor DNA in colorectal liver metastases: concordance with metastatic tissue and predictive value for tumor burden and prognosis

Y He, X Ma, K Chen, F Liu, S Cai… - Cancer management …, 2020 - Taylor & Francis
Background The surgical resection of colorectal cancer with liver metastases (CLM) has
proven to be the most important modality for long-term survival, while effective biomarkers …

[HTML][HTML] Circulating tumour DNA as a biomarker in resectable and irresectable stage IV colorectal cancer; a systematic review and meta-analysis

RP Jones, SA Pugh, J Graham, JN Primrose… - European Journal of …, 2021 - Elsevier
Background For patients with metastatic colorectal cancer, stratification for treatment
(surgery or chemotherapy) is often based on crude clinicopathological characteristics like …