Pancreatic adenocarcinoma and pancreatic high-grade neuroendocrine carcinoma: Two sides of the moon

A La Salvia, I Persano, E Parlagreco, A Audisio… - Medical Oncology, 2022 - Springer
Pancreatic adenocarcinoma is the seventh leading cause of cancer death in the world and
the most common type pf pancreatic cancer. Unfortunately, less than 20% of patients are …

Multidisciplinary Approach for the Management of Metastatic Poorly Differentiated Neuroendocrine Carcinoma of the Pancreas: A Case Report of an Exceptional …

ES Nakasone, HC Bustillos, X Gui, EQ Konnick… - Pancreas, 2024 - journals.lww.com
Poorly differentiated pancreatic neuroendocrine carcinomas (pNECs) are rare, highly
aggressive neoplasms. Frequently metastatic at diagnosis, prognosis is poor with median …

[HTML][HTML] Management of neuroendocrine carcinomas of the pancreas (WHO G3): A tailored approach between proliferation and morphology

S Crippa, S Partelli, G Belfiori, M Palucci… - World journal of …, 2016 - ncbi.nlm.nih.gov
Neuroendocrine carcinomas (NEC) of the pancreas are defined by a mitotic count> 20
mitoses/10 high power fields and/or Ki67 index> 20%, and included all the tumors …

[HTML][HTML] Pancreatic neuroendocrine neoplasms: survival trend analysis of a comprehensive center

S Coelho, C Costa, AP Santos, P Souteiro… - Endocrine …, 2022 - eo.bioscientifica.com
Objectives Therapeutic options for pancreatic neuroendocrine neoplasia (Pan-NEN) have
increased over the last decade. We aim to understand the evolution of the prognosis of …

Treatment of poorly differentiated neuroendocrine carcinoma of the pancreas

A Gupta, M Duque, MW Saif - JOP. Journal of the Pancreas, 2013 - serena.unina.it
Poorly differentiated neuroendocrine carcinoma is a rare malignancy that remains a
challenge to treat. Poorly differentiated neuroendocrine carcinoma occurs at an incidence of …

Non-functional neuroendocrine carcinoma of the pancreas: incidence, tumor biology, and outcomes in 2,158 patients

J Franko, W Feng, L Yip, E Genovese… - Journal of Gastrointestinal …, 2010 - Elsevier
Objective Pancreatic neuroendocrine cancer is a rare, indolent malignancy with no effective
systemic therapy currently available. This population-based analysis evaluated the …

Targeted therapies provide treatment options for poorly differentiated pancreatic neuroendocrine carcinomas

M Gilabert, YS Rho, P Kavan - Oncology, 2017 - karger.com
Poorly differentiated pancreatic neuroendocrine carcinoma (PD pNECs) is a rare disease
that has a poor prognosis and is treated with systemic chemotherapy as the standard of …

Pathology and surgical treatment of high-grade pancreatic neuroendocrine carcinoma: an evolving landscape

SP Haugvik, D Kaemmerer, S Gaujoux, KJ Labori… - Current oncology …, 2016 - Springer
Pancreatic neuroendocrine neoplasms (PNENs) are rare, accounting for less than 5% of all
pancreatic tumors. High-grade pancreatic neuroendocrine carcinomas (hgPNECs) …

Long-term outcomes and prognostic factors in neuroendocrine carcinomas of the pancreas: morphology matters

S Crippa, S Partelli, C Bassi, R Berardi, P Capelli… - Surgery, 2016 - Elsevier
Background Limited data are available for pancreatic neuroendocrine carcinomas (NEC)
defined by 2010 World Health Organization (WHO) criteria (mitotic count> 20 mitoses/10 …

[HTML][HTML] Pancreatic neuroendocrine tumors G3 and pancreatic neuroendocrine carcinomas: Differences in basic biology and treatment

MY Zhang, D He, S Zhang - World Journal of Gastrointestinal …, 2020 - ncbi.nlm.nih.gov
Abstract In 2017 the World Health Organization revised the criteria for classification of
pancreatic neuroendocrine neoplasms (pNENs) after a consensus conference at the …