[PDF][PDF] Resistin and visfatin: regulators of insulin sensitivity, inflammation and immunity

A Stofkova - Endocr Regul, 2010 - researchgate.net
Adipokines play a significant role in the pathogenesis of a low-grade inflammation
associated with obesity and metabolic syndrome, and in chronic inflammatory and …

Visfatin/PBEF/Nampt and resistin expressions in circulating blood monocytes are differentially related to obesity and type 2 diabetes in humans

M Laudes, F Oberhauser, DM Schulte… - Hormone and …, 2010 - thieme-connect.com
Low-grade inflammation is important in the development of obesity related pathologies such
as insulin resistance and type 2 diabetes, and also cardiovascular disease …

Resistin-and obesity-associated metabolic diseases

MA Lazar - Hormone and Metabolic Research, 2007 - thieme-connect.com
The link between obesity and diabetes is strong as well as complex. Fat cells produce many
circulating regulators of insulin sensitivity, including pro-inflammatory cytokines. In rodents …

Leptin, resistin and visfatin: the missing link between endocrine metabolic disorders and immunity

EA Al-Suhaimi, A Shehzad - European journal of medical research, 2013 - Springer
Adipose tissue is still regarded as a principle site for lipid storage and mobilizing tissue with
an important role in the control of energy homeostasis. Additionally, adipose tissue-secreted …

Resistin: an inflammatory cytokine. Role in cardiovascular diseases, diabetes and the metabolic syndrome

N Abate, HS Sallam, M Rizzo, D Nikolic… - Current …, 2014 - ingentaconnect.com
Resistin is an adipocyte-and monocyte-derived cytokine which has been implicated in the
modulation of insulin action, energy, glucose and lipid homeostasis. Resistin has been …

Proinflammatory cytokine production and insulin sensitivity regulated by overexpression of resistin in 3T3-L1 adipocytes

Y Fu, L Luo, N Luo, WT Garvey - Nutrition & metabolism, 2006 - Springer
Resistin is secreted from adipocytes, and high circulating levels have been associated with
obesity and insulin resistance. To investigate whether resistin could exert autocrine effects in …

Visfatin is regulated by rosiglitazone in type 2 diabetes mellitus and influenced by NFκB and JNK in human abdominal subcutaneous adipocytes

KC McGee, AL Harte, NF da Silva, N Al-Daghri… - PLoS one, 2011 - journals.plos.org
Visfatin has been proposed as an insulin-mimicking adipocytokine, predominantly secreted
from adipose tissue and correlated with obesity. However, recent studies suggest visfatin …

Resistin, an adipokine with potent proinflammatory properties

M Bokarewa, I Nagaev, L Dahlberg, U Smith… - The Journal of …, 2005 - journals.aai.org
The adipokine resistin is suggested to be an important link between obesity and insulin
resistance. In the present study, we assessed the impact of resistin as inflammatogenic …

Adipocytokines: leptin—the classical, resistin—the controversical, adiponectin—the promising, and more to come

A Koerner, J Kratzsch, W Kiess - Best practice & research Clinical …, 2005 - Elsevier
With the growing prevalence of obesity, scientific interest in the biology of adipose tissue has
been extended to the secretory products of adipocytes, since they are increasingly shown to …

Macrophage-derived human resistin exacerbates adipose tissue inflammation and insulin resistance in mice

M Qatanani, NR Szwergold… - The Journal of …, 2009 - Am Soc Clin Investig
Resistin is an adipokine that contributes to insulin resistance in mice. In humans, however,
studies investigating the link between resistin and metabolic disease are conflicting. Further …