Background & Aims Perpetuate liver inflammation is crucial in the pathogenesis of non-
alcoholic steatohepatitis (NASH). Expression of CXCL10, a pro-inflammatory cytokine …

Nonalcoholic steatohepatitis (NASH) is an inflammatory lipotoxic disorder, but how
inflammatory cells are recruited and activated within the liver is still unclear. We previously …

Background & Aims CXC chemokine receptor 3 (CXCR3) is involved in virus-related chronic
liver inflammation. However, the role of CXCR3 in non-alcoholic steatohepatitis (NASH) …

Non-alcoholic fatty liver disease (NAFLD) is a major cause of morbidity and mortality in
developed countries, resulting in steatohepatitis (NASH), fibrosis and eventually cirrhosis …

Background & Aims The number of patients with non-alcoholic steatohepatitis (NASH) is
increasing globally. Recently, specific chemokine receptors have garnered interest as …

Background and objectives Chemokine (C-X3-C motif) ligand 1 (CX3CL1) and its receptor
CX3CR1 regulate the migration and activation of immune cells and are involved in the …

Chemokines, such as CXCL10, promote hepatic inflammation in chronic or acute liver injury
through recruitment of leukocytes to the liver parenchyma. The CXCL10 receptor CXCR3 …

Background and Aims Nonalcoholic fatty liver disease encompasses a spectrum of diseases
ranging from simple steatosis to nonalcoholic steatohepatitis (NASH), cirrhosis, and liver …

Inflammatory cell infiltration in the liver is a hallmark of nonalcoholic steatohepatitis (NASH).
The chemokine-chemokine receptor interaction induces inflammatory cell recruitment. CC …

Non-alcoholic fatty liver disease (NAFLD) encompasses a wide spectrum of disease
severity, starting from pure steatosis, leading to fatty inflammation labeled as non-alcoholic …