The immunomodulatory and anti-inflammatory effect of curcumin on immune cell populations, cytokines, and in vivo models of rheumatoid arthritis

S Makuch, K Więcek, M Woźniak - Pharmaceuticals, 2021 - mdpi.com
Rheumatoid arthritis (RA) is a widespread chronic autoimmune disorder affecting the joints,
causing irreversible cartilage, synovium, and bone degradation. During the course of the …

Immunomodulatory effects of curcumin in rheumatoid arthritis: evidence from molecular mechanisms to clinical outcomes

S Mohammadian Haftcheshmeh, A Khosrojerdi… - Reviews of physiology …, 2021 - Springer
Rheumatoid arthritis (RA) is a chronic immune-mediated inflammatory disorder
characterized by the destruction of the joint and bone resorption. The production of pro …

Curcumin attenuates inflammatory response in IL-1β-induced human synovial fibroblasts and collagen-induced arthritis in mouse model

DO Moon, MO Kim, YH Choi, YM Park… - International …, 2010 - Elsevier
Curcumin, a major component of turmeric, has been shown to exhibit anti-oxidant and anti-
inflammatory activities. The present study was performed to determine whether curcumin is …

Anti-inflammatory effect of different curcumin preparations on adjuvant-induced arthritis in rats

I Rinkunaite, E Simoliunas, M Alksne… - … medicine and therapies, 2021 - Springer
Background Curcumin, a natural polyphenolic substance, has been known for more than
two millennia as having strong anti-inflammatory activity towards multiple ailments, including …

Curcumin alleviates rheumatoid arthritis progression through the phosphatidylinositol 3-kinase/protein kinase B pathway: an in vitro and in vivo study

Z Xu, W Shang, Z Zhao, B Zhang, C Liu, H Cai - Bioengineered, 2022 - Taylor & Francis
Rheumatoid arthritis (RA) is a chronic, systemic autoimmune disease characterized by
synovial inflammation and joint bone and cartilage destruction. Curcumin can improve joint …

Immunomodulatory effects of curcumin in systemic autoimmune diseases

S Chamani, M Moossavi, A Naghizadeh… - Phytotherapy …, 2022 - Wiley Online Library
Systemic autoimmune diseases like rheumatoid arthritis, multiple sclerosis, and systemic
lupus erythematosus represent various autoimmune conditions identified by immune system …

Curcumin and rheumatoid arthritis: A systematic review of literature

F Pourhabibi‐Zarandi… - … Journal of Clinical …, 2021 - Wiley Online Library
Background Curcumin is a natural polyphenol and the main compound from the rhizome of
Turmeric (Curcuma longa) and other Curcuma species. It has been widely used for different …

Therapeutic effects of curcumin in inflammatory and immune‐mediated diseases: A nature‐made jack‐of‐all‐trades?

E Abdollahi, AA Momtazi, TP Johnston… - Journal of cellular …, 2018 - Wiley Online Library
Curcumin is a dietary polyphenol from turmeric with numerous pharmacological activities.
Novel animal and human studies indicate that curcumin can affect different immune cells …

The spice for joint inflammation: anti-inflammatory role of curcumin in treating osteoarthritis

KY Chin - Drug design, development and therapy, 2016 - Taylor & Francis
Osteoarthritis is a degenerative disease of the joint affecting aging populations worldwide. It
has an underlying inflammatory cause, which contributes to the loss of chondrocytes …

Curcumin: A natural modulator of immune cells in systemic lupus erythematosus

AA Momtazi-Borojeni, SM Haftcheshmeh… - Autoimmunity …, 2018 - Elsevier
Curcumin is a polyphenol natural product isolated from turmeric, interacting with different
cellular and molecular targets and, consequently, showing a wide range of pharmacological …