Fecal microbiota transplantation promotes reduction of antimicrobial resistance by strain replacement

MH Woodworth, RE Conrad, M Haldopoulos… - Science translational …, 2023 - science.org
Multidrug-resistant organism (MDRO) colonization is a fundamental challenge in
antimicrobial resistance. Limited studies have shown that fecal microbiota transplantation …

Identification of clinical and ecological determinants of strain engraftment after fecal microbiota transplantation using metagenomics

D Podlesny, M Durdevic, S Paramsothy… - Cell Reports …, 2022 - cell.com
Fecal microbiota transplantation (FMT) is a promising therapeutic approach for microbiota-
associated pathologies, but our understanding of the post-FMT microbiome assembly …

Fecal microbiota transplantation for multidrug-resistant organism: efficacy and response prediction

H Seong, SK Lee, JH Cheon, DE Yong, H Koh… - Journal of Infection, 2020 - Elsevier
Objectives The increasing prevalence of multidrug-resistant microorganisms (MDRO) is
increasing the frequency of poor clinical outcomes, prolonging hospitalizations, and raising …

Disease prevention not decolonization: a model for fecal microbiota transplantation in patients colonized with multidrug-resistant organisms

R Ghani, BH Mullish, JAK McDonald… - Clinical Infectious …, 2021 - academic.oup.com
Fecal microbiota transplantation (FMT) yields variable intestinal decolonization results for
multidrug-resistant organisms (MDROs). This study showed significant reductions in …

Precise quantification of bacterial strains after fecal microbiota transplantation delineates long-term engraftment and explains outcomes

V Aggarwala, I Mogno, Z Li, C Yang, GJ Britton… - Nature …, 2021 - nature.com
Fecal microbiota transplantation (FMT) has been successfully applied to treat recurrent
Clostridium difficile infection in humans, but a precise method to measure which bacterial …

Tracking microbial colonization in fecal microbiota transplantation experiments via genome-resolved metagenomics

STM Lee, SA Kahn, TO Delmont, A Shaiber, ÖC Esen… - Microbiome, 2017 - Springer
Background Fecal microbiota transplantation (FMT) is an effective treatment for recurrent
Clostridium difficile infection and shows promise for treating other medical conditions …

Variability of strain engraftment and predictability of microbiome composition after fecal microbiota transplantation across different diseases

G Ianiro, M Punčochář, N Karcher, S Porcari… - Nature Medicine, 2022 - nature.com
Fecal microbiota transplantation (FMT) is highly effective against recurrent Clostridioides
difficile infection and is considered a promising treatment for other microbiome-related …

The trans-kingdom battle between donor and recipient gut microbiome influences fecal microbiota transplantation outcome

N Kazemian, M Ramezankhani, A Sehgal, FM Khalid… - Scientific reports, 2020 - nature.com
Fundamental restoration ecology and community ecology theories can help us better
understand the underlying mechanisms of fecal microbiota transplantation (FMT) and to …

Fecal microbiota transplantation in patients with blood disorders inhibits gut colonization with antibiotic-resistant bacteria: results of a prospective, single-center study

J Bilinski, P Grzesiowski, N Sorensen… - Clinical Infectious …, 2017 - academic.oup.com
Background Patients with blood disorders colonized with antibiotic-resistant bacteria (ARB)
are prone to systemic infections that are difficult to treat. Reintroduction of commensal …

[HTML][HTML] Faecal microbiota transplantation for eradicating carriage of multidrug-resistant organisms: a systematic review

S Saha, R Tariq, PK Tosh, DS Pardi… - Clinical Microbiology and …, 2019 - Elsevier
Background Multidrug-resistant (MDR) microorganism development in the gut is frequently
the result of inappropriate antibiotic use. Faecal microbiota transplantation (FMT) restores …