Hierarchical genetic networks and noncoding RNAs
VP Zhdanov - Chaos: An Interdisciplinary Journal of Nonlinear …, 2010 - pubs.aip.org
In eukaryotic cells, many genes are transcribed into noncoding RNAs. Such RNAs may
associate with mRNAs and inhibit their translation and facilitate degradation. To clarify what …
associate with mRNAs and inhibit their translation and facilitate degradation. To clarify what …
Non-coding RNAs and a layered architecture of genetic networks
VP Zhdanov - Central European Journal of Physics, 2010 - Springer
In eukaryotic cells, protein-coding sequences constitute a relatively small part of the
genome. The rest of the genome is transcribed to non-coding RNAs (ncRNAs). Such RNAs …
genome. The rest of the genome is transcribed to non-coding RNAs (ncRNAs). Such RNAs …
Non-coding RNAs and complex distributed genetic networks
V Zhdanov - Open Physics, 2011 - degruyter.com
In eukaryotic cells, the mRNA-protein interplay can be dramatically influenced by non-
coding RNAs (ncRNAs). Although this new paradigm is now widely accepted, an …
coding RNAs (ncRNAs). Although this new paradigm is now widely accepted, an …
ncRNA-mediated bistability in the synthesis of hundreds of distinct mRNAs and proteins
VP Zhdanov - Physica A: Statistical Mechanics and its Applications, 2010 - Elsevier
The kinetics of gene expression can be bistable due to the feedback between the mRNA
and protein formation. In eukaryotic cells, the interplay between mRNAs and proteins can be …
and protein formation. In eukaryotic cells, the interplay between mRNAs and proteins can be …
Kinetic models of gene expression including non-coding RNAs
VP Zhdanov - Physics Reports, 2011 - Elsevier
In cells, genes are transcribed into mRNAs, and the latter are translated into proteins. Due to
the feedbacks between these processes, the kinetics of gene expression may be complex …
the feedbacks between these processes, the kinetics of gene expression may be complex …
Bistability in a stochastic RNA-mediated gene network
J Lloyd-Price, AS Ribeiro - Physical Review E—Statistical, Nonlinear, and Soft …, 2013 - APS
Small regulatory RNAs (srRNAs) are important regulators of gene expression in eukaryotes
and prokaryotes. A common motif containing srRNA is a bistable two-gene motif where one …
and prokaryotes. A common motif containing srRNA is a bistable two-gene motif where one …
Noise and multistability in gene regulatory networks
EM Ozbudak - 2004 - dspace.mit.edu
Proteins are the functional machinery in living cells. Proteins interact with each other and
bind to DNA to form so-called gene regulatory networks and in this way regulate the level …
bind to DNA to form so-called gene regulatory networks and in this way regulate the level …
Monostability, bistability, periodicity and chaos in gene regulatory network
Q Lai, XW Zhao, JN Huang, VT Pham… - The European Physical …, 2018 - Springer
This letter gives a general review on the monostability, bistability, periodicity and chaos in
gene regulatory network. Some simple motifs that generate monostability, bistability …
gene regulatory network. Some simple motifs that generate monostability, bistability …
Effect of non-coding RNA on bistability and oscillations in the mRNA-protein interplay
VP Zhdanov - Biophysical Reviews and Letters, 2010 - World Scientific
The feedbacks between the mRNA and protein synthesis may result in kinetic bistability and
oscillations. Two generic models predicting bistability include, respectively, a gene with …
oscillations. Two generic models predicting bistability include, respectively, a gene with …
Bistability in gene transcription: interplay of messenger RNA, protein, and nonprotein coding RNA
VP Zhdanov - Biosystems, 2009 - Elsevier
The author proposes a kinetic model describing the interplay of messenger ribonucleic acid
(mRNA), protein, produced via translation of this RNA, and nonprotein coding RNA (ncRNA) …
(mRNA), protein, produced via translation of this RNA, and nonprotein coding RNA (ncRNA) …