Adenosine receptors modulate neuronal and synaptic function in a range of ways that may
make them relevant to the occurrence, development and treatment of brain ischemic …

A. Cellular and Subcellular Localization B. Pharmacological Tools to Study Adenosine
Receptors C. Signaling Via Adenosine Receptors D. Regulation of Receptor Expression and …

Protection against neuronal damage is a major objective of current research in areas such
as stroke medicine, Alzheimer's disease and other neurodegenerative conditions …

Adenosine is released from most cells, including neurons and glial cells. Once in the
extracellular space, adenosine modifies cell functioning by operating G-protein-coupled …

Adenosine acts in parallel as a neuromodulator and as a homeostatic modulator in the
central nervous system. Its neuromodulatory role relies on a balanced activation of inhibitory …

This review summarizes recent developments that have contributed to understand how
adenosine receptors, particularly A2A receptors, modulate brain injury in various animal …

Adenosine is a ubiquitous chemical messenger that modulates cellular activity in both the
CNS and peripheral organs. 1-5 Adenosine levels in the brain extracellular space increase …

DARÉ E, SCHULTE G, KAROVIC O, HAMMARBERG C, FREDHOLM BB. Modulation of glial
cell functions by adenosine receptors. PHYSIOL. BEHAV. 000-000, 2006. Adenosine is an …

Adenosine is present in the extacellular space of organs and tissues in the mammalian
organism where it modulates a variety of physiological processes through specific cell …

Adenosine A2B and, much more importantly, adenosine A2A receptors modulate many
physiological and pathological processes in the brain. In this review, the most recent …