MiRNA dysregulation in childhood hematological cancer

J Carvalho de Oliveira, G Molinari Roberto… - International journal of …, 2018 - mdpi.com
For decades, cancer biology focused largely on the protein-encoding genes that have clear
roles in tumor development or progression: cell-cycle control, apoptotic evasion, genome …

miRNA-mediated deregulation in leukemia

C Dell'Aversana, L Altucci - Frontiers in Genetics, 2012 - frontiersin.org
MicroRNAs (miRNAs) are small non-coding RNAs 18–25 nucleotides (nt) long able to fine-
tune post-transcriptional gene expression. Extensive investigation into biogenesis …

microRNAs: key players in hematopoiesis

HK Karnati, S Raghuwanshi, S Sarvothaman… - … : Basic Science: From …, 2015 - Springer
Abstract microRNAs (miRNAs) are small length noncoding RNAs which play a key role in
cellular processes such as proliferation, differentiation, and development of lineage …

Dysregulation of miRNA in leukemia: exploiting miRNA expression profiles as biomarkers

L Anelli, A Zagaria, G Specchia, P Musto… - International Journal of …, 2021 - mdpi.com
Micro RNAs (miRNAs) are a class of small non-coding RNAs that have a crucial role in
cellular processes such as differentiation, proliferation, migration, and apoptosis. miRNAs …

MicroRNAs in hematological malignancies: a novel approach to targeted therapy

D Joshi, K Gosh, BR Vundinti - Hematology, 2012 - Taylor & Francis
Abstract MicroRNAs (miRNAs) are about 19–24 nucleotide small single-stranded noncoding
RNAs that are involved in crucial cell processes such as proliferation, apoptosis, and …

Implication of microRNAs in carcinogenesis with emphasis on hematological malignancies and clinical translation

Z Gaál - International Journal of Molecular Sciences, 2022 - mdpi.com
MicroRNAs (miRNAs) are evolutionarily conserved small non-coding RNAs, that are
involved in the multistep process of carcinogenesis, contributing to all established hallmarks …

MiRNAs in hematopoiesis and acute lymphoblastic leukemia

DK Mendiola-Soto, DA Bárcenas-López… - International Journal of …, 2023 - mdpi.com
Acute lymphoblastic leukemia (ALL) is the most common kind of pediatric cancer. Although
the cure rates in ALL have significantly increased in developed countries, still 15–20% of …

MicroRNAs in myeloid hematological malignancies

M Ciccone, G Adrian Calin - Current genomics, 2015 - ingentaconnect.com
MicroRNAs are 19-24 nucleotides noncoding RNAs which silence modulate the expression
of target genes by binding to the messenger RNAs. Myeloid malignancies include a broad …

MicroRNAs in cancer: personalizing diagnosis and therapy

SP Nana‐Sinkam, M Fabbri… - Annals of the New York …, 2010 - Wiley Online Library
MicroRNAs (miRNAs) are 19–24nt noncoding RNAs that have been implicated in the
pathogenesis of both solid and hematological malignancies. Frequently located in fragile …

New insight into the role of miRNAs in leukemia

H Zhang, YQ Chen - Science in China Series C: Life Sciences, 2009 - Springer
Recent studies have shown that microRNAs (miRNAs) play an important role in cell
differentiation, growth, and death, including the functional study of miRNAs in tumorigenesis …