Cytoskeletal crosstalk in cell migration

S Seetharaman, S Etienne-Manneville - Trends in cell biology, 2020 - cell.com
Cell migration is a highly dynamic process driven by the cytoskeleton, which mainly
comprises the actin microfilaments, microtubules, and intermediate filaments. During …

Actin, microtubules and focal adhesion dynamics during cell migration

B Wehrle-Haller, BA Imhof - The international journal of biochemistry & cell …, 2003 - Elsevier
Cell migration is a complex cellular behavior that results from the coordinated changes in
the actin cytoskeleton and the controlled formation and dispersal of cell-substrate adhesion …

Actin dynamics and turnover in cell motility

K Rottner, TEB Stradal - Current opinion in cell biology, 2011 - Elsevier
Cell migration is a highly coordinated process involving a multitude of separable but
intertwined phenomena traditionally studied in multiple cell types, tissues and model …

Mechanical integration of actin and adhesion dynamics in cell migration

ML Gardel, IC Schneider… - Annual review of cell …, 2010 - annualreviews.org
Directed cell migration is a physical process that requires dramatic changes in cell shape
and adhesion to the extracellular matrix. For efficient movement, these processes must be …

Cell adhesion: integrating cytoskeletal dynamics and cellular tension

JT Parsons, AR Horwitz, MA Schwartz - Nature reviews Molecular cell …, 2010 - nature.com
Cell migration affects all morphogenetic processes and contributes to numerous diseases,
including cancer and cardiovascular disease. For most cells in most environments …

Mechanoreciprocity in cell migration

S Van Helvert, C Storm, P Friedl - Nature cell biology, 2018 - nature.com
Cell migration is an adaptive process that depends on and responds to physical and
molecular triggers. Moving cells sense and respond to tissue mechanics and induce …

Microtubules and actin crosstalk in cell migration and division

TK Akhshi, D Wernike, A Piekny - Cytoskeleton, 2014 - Wiley Online Library
Crosstalk between the actin cytoskeleton and microtubules promotes symmetry break to
polarize cells for division, shape changes, and migration. These cellular events are crucial …

Actin dynamics in cell migration

M Schaks, G Giannone, K Rottner - Essays in biochemistry, 2019 - portlandpress.com
Cell migration is an essential process, both in unicellular organisms such as amoeba and as
individual or collective motility in highly developed multicellular organisms like mammals. It …

Signaling networks that regulate cell migration

P Devreotes, AR Horwitz - Cold Spring Harbor …, 2015 - cshperspectives.cshlp.org
Stimuli that promote cell migration, such as chemokines, cytokines, and growth factors in
metazoans and cyclic AMP in Dictyostelium, activate signaling pathways that control …

Regulation of actin assembly associated with protrusion and adhesion in cell migration

C Le Clainche, MF Carlier - Physiological reviews, 2008 - journals.physiology.org
To migrate, a cell first extends protrusions such as lamellipodia and filopodia, forms
adhesions, and finally retracts its tail. The actin cytoskeleton plays a major role in this …