Bone marrow–and adult kidney–derived stem/progenitor cells hold promise in the
development of therapies for renal failure. Here is reported the identification and …

Regenerative medicine represents a critical clinical goal for patients with ESRD, but the
identification of renal adult multipotent progenitor cells has remained elusive. It is …

Identification of tissue‐specific renal stem/progenitor cells with nephrogenic potential is a
critical step in developing cell‐based therapies for renal disease. In the human kidney …

We describe here isolation and characterization of CD133+ cells derived from normal adult
human kidney. These cells lacked the expression of hematopoietic markers and expressed …

Recent studies implicated the existence in adult human kidney of a population of renal
progenitors with the potential to regenerate glomerular as well as tubular epithelial cells and …

In most adult epithelia the process of replacing damaged or dead cells is maintained
through the presence of stem/progenitor cells, which allow epithelial tissues to be repaired …

The ability of the human kidney to repair itself is limited. Consequently, repeated injury can
trigger a maladaptive response that is characterized by fibrosis and loss of renal function …

Acute kidney injury is followed by regeneration of damaged renal tubular epithelial cells.
The purpose of this study was to test the hypothesis that renal stem cells exist in the adult …

End-stage renal disease (ESRD) is defined as the inability of the kidneys to remove waste
products and excess fluid from the blood. ESRD progresses from earlier stages of chronic …

Tissue engineering and cell therapy approaches aim to take advantage of the repopulating
ability and plasticity of multipotent stem cells to regenerate lost or diseased tissue. Recently …