Endothelial cells (ECs) maintain the health of blood vessels and prevent the development of
cardiovascular disease (CVD). Free saturated fatty acids (FAs) induce EC damage and …

Background: Prospective cohort studies and randomized controlled trials have shown the
protective effect of n-3 fatty acids against cardiovascular disease (CVD). The effect of n-3 …

The endothelium is critical for the maintenance of a proper vessel function. Disturbances of
endothelial function, called endothelial dysfunction, have serious implications, and lead to …

Plasma free fatty acids levels are increased in subjects with obesity and type 2 diabetes,
playing detrimental roles in the pathogenesis of atherosclerosis and cardiovascular …

The endothelium acts as the barrier that prevents circulating lipids such as lipoproteins and
fatty acids into the arterial wall; it also regulates normal functioning in the circulatory system …

since inflammation is the final common pathway/mechanism underlying atherosclerosis.
Thus, increased concentrations of FFA in plasma could also contribute to atherogenesis …

Recent studies have shown that free fatty acids are associated with chronic inflammation,
which may be involved in vascular injury. The intake of eicosapentaenoic acid (EPA) can …

Healthy and functional endothelial cells play important roles in maintaining vascular
homeostasis, whereas endothelial dysfunction initiates and exacerbates vascular disease …

Omega-3 fatty acids, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), and to
a limited extent ω-6 fatty acids: arachidonic acid (AA), γ-linolenic acid (GLA) and dihomo …

Scope Dietary fat composition is an important modulator of vascular function. Non-esterified
fatty acids (NEFA) enriched in saturated fatty acids (SFA) are thought to reduce vascular …