Impact of a single round of mass drug administration with azithromycin on active trachoma and ocular Chlamydia trachomatis prevalence and circulating strains in …

EM Harding-Esch, MJ Holland, JF Schémann… - Parasites & vectors, 2019 - Springer
Background Mass drug administration (MDA) with azithromycin is a cornerstone of the
trachoma elimination strategy. Although the global prevalence of active trachoma has …

Number of years of annual mass treatment with azithromycin needed to control trachoma in hyper-endemic communities in Tanzania

SK West, B Munoz, H Mkocha… - Journal of Infectious …, 2011 - academic.oup.com
Abstract Background. The World Health Organization recommends mass treatment as part of
a trachoma control strategy. However, scant empirical data from hyperendemic communities …

The impact of a single round of community mass treatment with azithromycin on disease severity and ocular Chlamydia trachomatis load in treatment-naïve trachoma …

AR Last, SE Burr, E Harding-Esch, E Cassama… - Parasites & vectors, 2017 - Springer
Background Trachoma, a neglected tropical disease, is caused by ocular infection with
Chlamydia trachomatis (Ct). The World Health Organization (WHO) recommends three …

Risk factors for ocular chlamydia after three mass azithromycin distributions

B Ayele, T Gebre, J Moncada, JI House… - PLoS neglected …, 2011 - journals.plos.org
Background An important component of the World Health Organization's comprehensive
trachoma elimination strategy is the provision of repeated annual mass azithromycin …

Reduction and return of infectious trachoma in severely affected communities in Ethiopia

T Lakew, J House, KC Hong, E Yi… - PLoS neglected …, 2009 - journals.plos.org
Background Antibiotics are a major tool in the WHO's trachoma control program. Even a
single mass distribution reduces the prevalence of the ocular chlamydia that causes …

[HTML][HTML] Prevalence of ocular Chlamydia trachomatis infection in Amhara region, Ethiopia, after 8 years of trachoma control interventions

SD Nash, A Chernet, P Weiss, AW Nute… - The American Journal …, 2023 - ncbi.nlm.nih.gov
Although trachoma mass drug administration (MDA) programs target ocular Chlamydia
trachomatis, the global trachoma control program does not monitor infection as a measure of …

Is There Evidence for Resistance of Ocular Chlamydia trachomatis to Azithromycin After Mass Treatment for Trachoma Control?

SK West, J Moncada, B Munoz… - The Journal of …, 2014 - academic.oup.com
Background. Trachoma, caused by repeated infections with ocular Chlamydia trachomatis,
is targeted for elimination using multiple annual rounds of mass drug administration (MDA) …

Re-emergence of Chlamydia trachomatis infection after mass antibiotic treatment of a trachoma-endemic Gambian community: a longitudinal study

MJ Burton, MJ Holland, P Makalo, EAN Aryee… - The Lancet, 2005 - thelancet.com
Background Community-wide mass antibiotic treatment is a central component of trachoma
control. The optimum frequency and duration of treatment are unknown. We measured the …

Stopping azithromycin mass drug administration for trachoma: A systematic review

H Mahmud, E Landskroner, A Amza… - PLoS neglected …, 2021 - journals.plos.org
The World Health Organization (WHO) recommends continuing azithromycin mass drug
administration (MDA) for trachoma until endemic regions drop below 5% prevalence of …

Risk factors for active trachoma and Chlamydia trachomatis infection in rural Ethiopia after mass treatment with azithromycin

T Edwards, EM Harding‐Esch, G Hailu… - Tropical medicine & …, 2008 - Wiley Online Library
Objectives To investigate risk factors for ocular Chlamydia trachomatis infection and active
trachoma, comparing communities receiving or not receiving an intervention programme of …