Tren pemanfaatan peptida, suatu rantai pendek asam amino, sebagai terapi pengobatan
terus meningkat dalam beberapa dekade terakhir. Peptida terapetik biasanya …

Peptides are small polymers composed of 40 or fewer amino acids and are an increasingly
important class of drugs. Therapeutic peptides are less immunogenic and more economical …

Over the past few decades, there has been a tremendous increase in the utilization of
therapeutic peptides. Therapeutic peptides are usually administered via the parenteral …

Therapeutic peptides have high selectivity, efficacy, and low toxicity. These characteristics,
combined with advances in solid-phase peptide synthesis and purification methods, have …

Low oral bioavailability and shorter half-life. Peptide hydrophilicity is responsible for its poor
permeability through physiological barriers and biological membranes. In addition to, their …

Certain peptides are chemically unstable in aqueous parenteral formulations at pH 5-7 and
room temperature, largely because of reactive peptide sequences. The major degradation …

Peptide drugs represent 5% of the global pharmaceutical market, but growing twice as fast
as the rest of the drug market. The development of peptide therapeutics is challenging due …

Quality by design (QbD) serves as a systematic approach to pharmaceutical development,
beginning with predefined objectives and emphasizing an understanding of the product …

Proteins/peptides are generally much more sensitive to process‐or storage‐induced
degradations than small synthetic molecules. Therefore, significant efforts are needed to …