Sugar consumption is assumed to induce a behavioral state that is similar to the one
provoked by addictive substances. Drug withdrawal increases impulsivity, assessed by …

Studies have shown that intermittent sugar availability (12 h/day) produces signs of
dependence in rats, including escalation of intake, mu-opioid and dopamine receptor …

The high levels of drinking induced by intermittent food-reinforcement schedules are dose-
dependently reduced by acute doses of d-amphetamine. The present study evaluated …

Background: This study examined the associations among selective breeding for alcohol
preference, intake of sweet solutions, and responding for brain stimulation reward (BSR), a …

A sequence of studies sought to determine if 2-deoxy-D-glucose (2DG) produces malaise as
a side effect. Drug treatment at dosages at least as low as 250 mg/kg triggered an immediate …

Previous studies have shown that withdrawal from psychostimulant drugs such as d‐
amphetamine or methamphetamine decreases motivation to work for a natural …

Reward uncertainty can sensitize reward pathways, promoting increased reward-seeking
and-taking behaviours. This is relevant to human conditions such as pathological gambling …

The purpose of this study was to examine a form of impulsive behavior (impaired inhibition)
using cocaine or food reward in addiction-prone and addiction-resistant rats that were bred …

Free-fed rats were shifted from brief access to 32% sucrose (5 min per day for 3 days) to 4%
sucrose (5 min per day for 2 days) 8 separate times. During preshift, rats given access to …

Abstract Rationale Quinpirole (QNP), a D2/D3 dopaminergic receptor agonist, was found to
elicit an apparently antieconomical drinking behavior called contrafreeloading (CFL). The …