Cryptococcus neoformans, an encapsulated fungal pathogen, causes meningoencephalitis
in immunocompromised patients. Recent in vivo studies have demonstrated that C …

Cryptococcus neoformans is the causative agent of cryptococcosis and cryptococcal
meningitis, which are serious pathological conditions affecting up to 10% of patients with …

Cryptococcus neoformans (Cn) is a soil fungus that causes life-threatening meningitis in
immunocompromised patients and is a facultative intracellular pathogen capable of …

Cryptococcus neoformans is an encapsulated yeast and an opportunistic fungal pathogen
responsible for lifethreatening infections of the central nervous system (CNS) in HIV-1 …

Escape from the intravascular compartment is likely a critical step in the development of
hematogenously disseminated cryptococcal infections, such as meningitis. The capsule of …

Cryptococcus neoformans is a fungal pathogen that encounters various microenvironments
during growth in the mammalian host, including intracellular vacuoles, blood, and …

Life-threatening infections caused by the encapsulated fungal pathogen Cryptococcus
neoformans have been increasing steadily over the past 10 years because of the onset of …

Despite a presumed critical role of macrophages in the host response to cryptococcal
infections, previous studies have failed to show growth inhibition of encapsulated …

Brain infection by the fungus Cryptococcus neoformans results in inflammation of the
meninges and brain parenchyma, a condition known as meningoencephalitis. One million …

Background The interaction between macrophages and Cryptococcus neoformans (Cn) is
critical for containing dissemination of this pathogenic yeast. However, Cn can either lyse …