Importance Cannabis and cannabinoid drugs are widely used to treat disease or alleviate
symptoms, but their efficacy for specific indications is not clear. Objective To conduct a …

Objective To determine the effects of medical cannabinoids on pain, spasticity, and nausea
and vomiting, and to identify adverse events. Data sources MEDLINE, the Cochrane …

Background: The therapeutic use of cannabis and cannabis-based medicines raises safety
concerns for patients, clinicians, policy-makers, insurers, researchers and regulators …

Herbal cannabis has been used for thousands of years for medical purposes. With
elucidation of the chemical structures of tetrahydrocannabinol (THC) and cannabidiol (CBD) …

Cannabinoids are a diverse class of chemical compounds that are increasingly recognized
as potential therapeutic options for a range of conditions. While many studies and reviews of …

Background Medical cannabinoids differ in their pharmacology and may have different
treatment effects. We aimed to conduct a pharmacology-based systematic review (SR) and …

Cannabis is the most popular illicit drug in the Western world. Repeated cannabis use has
been associated with short‐and long‐term side effects, including respiratory and …

Background: Contemporary data are needed about the utility of cannabinoids in chronic
pain. Purpose: To evaluate the benefits and harms of cannabinoids for chronic pain. Data …

Chronic pain states have resulted in an overreliance on opioid pain relievers, which can
carry significant risks when used long term. As such, alternative pain treatments are …

Objective To develop a clinical practice guideline for a simplified approach to medical
cannabinoid use in primary care; the focus was on primary care application, with a strong …