BACKGROUND: Treatment of human bladder overactivity with intradetrusor Botulinum-A
neurotoxin (BoNT/A) injections temporarily blocks the presynaptic release of acetylcholine …

BACKGROUND: Botulinum neurotoxin A (BoNTA), which alleviates overactive bladder
symptoms, is thought to act predominantly via the inhibition of transmitter release from …

Purpose: Botulinum neurotoxin type A (BoNT/A) is effective in the treatment of intractable
detrusor overactivity (DO). In addition to its known inhibitory effect on presynaptic release of …

OBJECTIVE: In recent years there has been an increasing use of the botulinum neurotoxins
for the management of conditions characterised by detrusor overactivity. Early studies …

OBJECTIVE: Determine long-term effect of English botulinum neurotoxin type A (BoNTA;
Dysport®) for refractory neurogenic detrusor overactivity (NDO) for possible reduction of …

During the last few years, vanilloid substances and botulinum-A toxin were extensively
investigated as new therapies for overactive bladder. Intravesical administration of capsaicin …

Botulinum toxin is a presynaptic neuromuscular blocking agent inducing selective and
reversible muscle weakness up to several months when injected intramuscularly in minute …

Purpose: We evaluated the use of botulinum toxin-A in treating patients with idiopathic
detrusor overactivity refractory to anticholinergics. Materials and Methods: This double-blind …

Purpose: Several studies have shown that intradetrusor injections of botulinum neurotoxin
type A (BoNT/A) may effectively treat intractable spinal neurogenic detrusor overactivity …

OBJECTIVES: To investigate the clinical and urodynamic effects of suburothelial injection of
botulinum A toxin on patients with nonneurogenic detrusor overactivity. Intradetrusor …