[HTML][HTML] Alzheimer mechanisms and therapeutic strategies
There are still no effective treatments to prevent, halt, or reverse Alzheimer's disease, but
research advances over the past three decades could change this gloomy picture. Genetic …
research advances over the past three decades could change this gloomy picture. Genetic …
Alzheimer's disease: the challenge of the second century
DM Holtzman, JC Morris, AM Goate - Science translational medicine, 2011 - science.org
Alzheimer's disease (AD) was first described a little more than 100 years ago. It is the most
common cause of dementia with an estimated prevalence of 30 million people worldwide, a …
common cause of dementia with an estimated prevalence of 30 million people worldwide, a …
Pathophysiological aspects and therapeutic armamentarium of Alzheimer's disease: recent trends and future development
BP Dave, YB Shah, KG Maheshwari… - Cellular and Molecular …, 2023 - Springer
Alzheimer's disease (AD) is the primary cause of dementia and is characterized by the death
of brain cells due to the accumulation of insoluble amyloid plaques, hyperphosphorylation of …
of brain cells due to the accumulation of insoluble amyloid plaques, hyperphosphorylation of …
Alzheimer's disease: molecular understanding predicts amyloid-based therapeutics
DJ Selkoe, D Schenk - Annual review of pharmacology and …, 2003 - annualreviews.org
Degenerative diseases of the brain were long considered among the most obscure and
intractable of human maladies. However, recent advances in understanding their …
intractable of human maladies. However, recent advances in understanding their …
Molecular and cellular mechanisms underlying the pathogenesis of Alzheimer's disease
Alzheimer's disease (AD) is the most common neurodegenerative disorder seen in age-
dependent dementia. There is currently no effective treatment for AD, which may be …
dependent dementia. There is currently no effective treatment for AD, which may be …
Current progress, challenges and future prospects of diagnostic and therapeutic interventions in Alzheimer's disease
K Rajasekhar, T Govindaraju - RSC advances, 2018 - pubs.rsc.org
Alzheimer's disease (AD) is the most prevalent, progressive and multifaceted
neurodegenerative disorder associated with cognition, memory and behavioural …
neurodegenerative disorder associated with cognition, memory and behavioural …
Insights into the pathophysiology of Alzheimer's disease and potential therapeutic targets: A current perspective
K Rajah Kumaran, S Yunusa, E Perimal… - Journal of …, 2023 - content.iospress.com
The aging population increases steadily because of a healthy lifestyle and medical
advancements in healthcare. However, Alzheimer's disease (AD) is becoming more …
advancements in healthcare. However, Alzheimer's disease (AD) is becoming more …
Advances and challenges in the prevention and treatment of Alzheimer's disease
RD Brinton, RS Yamazaki - Pharmaceutical Research, 1998 - Springer
Alzheimer's disease (AD) is the most common cause of dementia and accounts for one-half
to three-fourths of all cases of dementia. In the United States, AD is the leading cause of a …
to three-fourths of all cases of dementia. In the United States, AD is the leading cause of a …
Alzheimer's disease; a review of the pathophysiological basis and therapeutic interventions
A Abeysinghe, R Deshapriya, C Udawatte - Life sciences, 2020 - Elsevier
Alzheimer's disease (AD) is a neurodegenerative disorder and is identified as the most
common cause for dementia. Despite huge global economic burden and the impact on the …
common cause for dementia. Despite huge global economic burden and the impact on the …
A critical analysis of new molecular targets and strategies for drug developments in Alzheimer's disease
DK Lahiri, MR Farlow, K Sambamurti… - Current drug …, 2003 - ingentaconnect.com
Alzheimer's disease (AD), a progressive, degenerative disorder of the brain, is believed to
be the most common cause of dementia amongst the elderly. AD is characterized by the …
be the most common cause of dementia amongst the elderly. AD is characterized by the …