Epidemiology of acromegaly
IM Holdaway, C Rajasoorya - Pituitary, 1999 - Springer
Acromegaly was defined as a syndrome by Pierre Marie in 1885, but in the form of either
acromegaly or acrogigantism has probably been a disorder of antiquity [1, 2]. It is one of the …
acromegaly or acrogigantism has probably been a disorder of antiquity [1, 2]. It is one of the …
[HTML][HTML] Updates in diagnosis and treatment of acromegaly
R Zahr, M Fleseriu - European endocrinology, 2018 - ncbi.nlm.nih.gov
Acromegaly is a rare disease, caused largely by a growth hormone (GH) pituitary adenoma.
Incidence is higher than previously thought. Due to increased morbidity and mortality, if not …
Incidence is higher than previously thought. Due to increased morbidity and mortality, if not …
Acromegaly: the disease, its impact on patients, and managing the burden of long-term treatment
DT Adelman, KJP Liebert, LB Nachtigall… - … journal of general …, 2013 - Taylor & Francis
Acromegaly is a rare disease most often caused by the prolonged secretion of excess
growth hormone from a pituitary adenoma. The disease is associated with multiple …
growth hormone from a pituitary adenoma. The disease is associated with multiple …
[引用][C] Clinical review 75: recent advances in pathogenesis, diagnosis, and management of acromegaly
S Melmed, K Ho, A Klibanski, S Reichlin… - The Journal of …, 1995 - academic.oup.com
The CLINICAL consequences of advanced acromegaly are disfigurement, disability, and
shortened life expectancy due to respiratory, metabolic, cardiovascular, and malignant …
shortened life expectancy due to respiratory, metabolic, cardiovascular, and malignant …
Acromegaly
A Colao, LFS Grasso, A Giustina, S Melmed… - Nature Reviews …, 2019 - nature.com
Acromegaly is characterized by increased release of growth hormone and, consequently,
insulin-like growth factor I (IGF1), most often by a pituitary adenoma. Prolonged exposure to …
insulin-like growth factor I (IGF1), most often by a pituitary adenoma. Prolonged exposure to …
[HTML][HTML] Acromegaly pathogenesis and treatment
S Melmed - The Journal of clinical investigation, 2009 - Am Soc Clin Investig
Dysregulated growth hormone (GH) hypersecretion is usually caused by a GH-secreting
pituitary adenoma and leads to acromegaly—a disorder of disproportionate skeletal, tissue …
pituitary adenoma and leads to acromegaly—a disorder of disproportionate skeletal, tissue …
Acromegaly
A Ben-Shlomo, S Melmed - Endocrinology and metabolism clinics of North …, 2008 - Elsevier
Acromegaly is a rare disease caused by growth hormone hypersecretion, mostly from a
pituitary adenoma, driving insulin-like growth factor 1 overproduction. Manifestations include …
pituitary adenoma, driving insulin-like growth factor 1 overproduction. Manifestations include …
[HTML][HTML] Acromegaly
P Chanson, S Salenave - Orphanet journal of rare diseases, 2008 - Springer
Acromegaly is an acquired disorder related to excessive production of growth hormone (GH)
and characterized by progressive somatic disfigurement (mainly involving the face and …
and characterized by progressive somatic disfigurement (mainly involving the face and …
Pathophysiology of acromegaly
S Melmed, GD Braunstein, EVA Horvath… - Endocrine …, 1983 - academic.oup.com
Introduction A CROMEGALY, a spectacular disorder of somatic growth and proportion, has
fascinated endocrinologists for the past century and was the first pituitary disorder to be …
fascinated endocrinologists for the past century and was the first pituitary disorder to be …