Therapies directed toward the central nervous system remain difficult to translate into
improved clinical outcomes. This is largely due to the blood–brain barrier (BBB), arguably …

The blood-brain barrier (BBB) is a highly regulated physical and functional boundary that
tightly controls the transport of materials between the blood and the brain. There is an …

The existence of blood–brain barrier (BBB) hampers the effective treatment of central
nervous system (CNS) diseases. Almost all macromolecular drugs and more than 98% of …

A major obstacle facing brain diseases such as Alzheimer's disease, multiple sclerosis,
brain tumors, and strokes is the blood–brain barrier (BBB). The BBB prevents the passage of …

The protective properties of the blood–brain barrier (BBB) are conferred by the intricate
architecture of its endothelium coupled with multiple specific transport systems expressed on …

In recent decades, research scientists, molecular biologists, and pharmacologists have
placed a strong emphasis on cutting-edge nanostructured materials technologies to …

Recent times have witnessed an upsurge in the incidence of neurodegenerative disorders
such as Alzheimer's disease, Parkinson's disease, Huntington's disease, Prion disease, and …

While the role of the blood-brain barrier (BBB) is increasingly recognized in the
(development of treatments targeting neurodegenerative disorders, to date, few strategies …

The intricate microstructure of the blood-brain barrier (BBB) is responsible for the accurate
intrinsic regulation of the central nervous system (CNS), in terms of neuronal …

We are now in an aging population, so neurological disorders, particularly the
neurodegenerative diseases, are becoming more prevalent in society. As per the …