γδT cells mature in the human thymus, and mainly produce IL-17A or IFN-γ, but can also
produce IL-22 and modulate a variety of immune responses. Here, we aimed to evaluate …

Atopic dermatitis (AD) is a common relapsing inflammatory skin disorder characterized by
immune-mediated inflammation and epidermal barrier dysfunction. The pathogenesis of AD …

Background The precise mechanism involved in the acquisition of the IL‐17+ profile of γδT
cells, the ligands responsible for this change, and whether this default is acquired during …

Introduction Our group recently demonstrated that IgG modulates αβT cell cytokine
production during the maturation process in the human thymus. The effects of this …

Matured in the thymus, γδT cells can modulate the development of allergy in humans. The
main γδT cell subsets have been described as interleukin (IL)-17A or interferon (IFN)-γ …

Atopic dermatitis (AD) is a chronic disease related to skin disorders that affect individuals in
their childhood and can persist or start in adulthood. Patients affected by this disease …

Background Atopic dermatitis (AD) pathogenesis still needs to be elucidated, but invariant
natural killer T (iNKT) cell involvement was already described by several groups. Our group …

Atopic Dermatitis (AD) is a T cell-mediated chronic skin disease and is associated with
altered skin barrier integrity. Infants with mutations in genes involved in tissue barrier fitness …

Atopic dermatitis (AD) is classified as a type 2 disease owing to the majority of type 2
lymphocytes that constitute the skin-infiltrating leukocytes. However, all of the type 1–3 …

Severe pruritus is a characteristic feature of atopic dermatitis (AD) and is closely related to its
activity. Recent studies have shown that IL-31 is a key determinant of pruritus in AD. Anti-IL …