Hypoxia is an important phenomenon due to insufficient oxygen supply in tumor tissue, and
nitroreductase (NTR) is a characteristic enzyme used for evaluating hypoxia level in tumors …

Tumor-selective accumulation of gold nanorods (GNR) has been demonstrated for
visualization of tumor hypoxia by photoacoustic imaging. We prepared GNRs with hypoxia …

Macrophage-mediated delivery of drugs or nanoparticles has great potential in cancer
treatment because it can avoid interception by the immune system and cross the blood …

Background Properly designed second near-infrared (NIR-II) nanoplatform that is
responsive tumor microenvironment can intelligently distinguish between normal and …

Microenvironment-responsive imaging has tremendous application potential in disease
diagnosis. Elevated levels of hydrogen peroxide (H2O2) have been observed in tumor and …

The acidic microenvironment of tumor tissues has been proven to be a major characteristic
for differentiation from normal tissues, thereby providing a desirable target for both disease …

By directly harming cancer cells, radiotherapy (RT) is a crucial therapeutic approach for the
treatment of cancers. However, the efficacy of RT is reduced by the limited accumulation and …

Photoacoustic imaging (PAI) is an invaluable tool in biomedical imaging, as it provides
anatomical and functional information in real time. Its ability to image at clinically relevant …

Gold nanorods (AuNRs) can be synthesised with different sizes but similar aspect ratios and
therefore similar surface plasmon resonances (SPRs). Their strong optical absorbance …

Photoacoustic tomography has emerged as a promising non-invasive imaging technique
that integrates the merits of high optical contrast with high ultrasound resolution in deep …