Statin treatment of children with familial hypercholesterolemia–trying to balance incomplete evidence of long-term safety and clinical accountability: are we …
A Vuorio, KF Docherty, SE Humphries, J Kuoppala… - Atherosclerosis, 2013 - Elsevier
In the heterozygous form of familial hypercholesterolemia (FH), blood concentrations of low-
density lipoprotein cholesterol (LDL-C) are elevated two to three times above the normal …
density lipoprotein cholesterol (LDL-C) are elevated two to three times above the normal …
A systematic review and meta-analysis of statin therapy in children with familial hypercholesterolemia
HJ Avis, MN Vissers, EA Stein, FA Wijburg… - … , and vascular biology, 2007 - Am Heart Assoc
Objective—Functional and morphological changes of the arterial wall already present in
young children with heterozygous familial hypercholesterolemia (HeFH) suggest that …
young children with heterozygous familial hypercholesterolemia (HeFH) suggest that …
Familial hypercholesterolemia in children and adolescents
BW McCrindle - Current opinion in lipidology, 2012 - journals.lww.com
Familial hypercholesterolemia in children and adolescents : Current Opinion in Lipidology
Familial hypercholesterolemia in children and adolescents : Current Opinion in Lipidology Log …
Familial hypercholesterolemia in children and adolescents : Current Opinion in Lipidology Log …
Efficacy and safety of statin use in children and adolescents with familial hypercholesterolaemia: a systematic review and meta-analysis of randomized-controlled trials
P Anagnostis, K Vaitsi, P Kleitsioti, C Mantsiou… - Endocrine, 2020 - Springer
Purpose Statins are the mainstay of treatment for patients with familial
hypercholesterolaemia (FH). However, their efficacy and safety in children and adolescents …
hypercholesterolaemia (FH). However, their efficacy and safety in children and adolescents …
Statin treatment for children and adolescents with heterozygous familial hypercholesterolaemia: a systematic review and meta-analysis
AIMS: To assess efficacy and safety of HMG-CoA reductase inhibitor (statin) treatment in
children and adolescents with heterozygous familial hypercholesterolaemia. METHODS …
children and adolescents with heterozygous familial hypercholesterolaemia. METHODS …
Systematic review and metaanalysis of statins for heterozygous familial hypercholesterolemia in children: evaluation of cholesterol changes and side effects
CS O'Gorman, MF Higgins, MB O'Neill - Pediatric cardiology, 2009 - Springer
Heterozygous familial hypercholesterolemia (heFH) affects 1 in 500 individuals. Evidence
supports the low-density lipoprotein (LDL)-lowering effect of statins for adults with heFH …
supports the low-density lipoprotein (LDL)-lowering effect of statins for adults with heFH …
Prevention of atherosclerotic cardiovascular disease in children with familial hypercholesterolemia
AL Peterson, CJ McNeal, DP Wilson - Current Atherosclerosis Reports, 2021 - Springer
Abstract Purpose of Review Familial hypercholesterolemia (FH), a common inherited
disorder of LDL-C metabolism that predisposes to premature cardiovascular disease, is …
disorder of LDL-C metabolism that predisposes to premature cardiovascular disease, is …
[HTML][HTML] The UK Paediatric Familial Hypercholesterolaemia Register: Statin-related safety and 1-year growth data
SE Humphries, J Cooper, P Dale, U Ramaswami… - Journal of Clinical …, 2018 - Elsevier
Background For children with familial hypercholesterolemia (FH), UK guidelines recommend
consideration of statin therapy by age 10 years and dietary and lifestyle advice to maintain …
consideration of statin therapy by age 10 years and dietary and lifestyle advice to maintain …
The knowns and unknowns of contemporary statin therapy for familial hypercholesterolemia
Abstract Purpose of Review Statins are first-line therapy for lowering low-density lipoprotein
(LDL) cholesterol in familial hypercholesterolemia (FH), particularly in heterozygous …
(LDL) cholesterol in familial hypercholesterolemia (FH), particularly in heterozygous …
Long-term follow-up of statin treatment in a cohort of children with familial hypercholesterolemia: efficacy and tolerability
V Carreau, JP Girardet, E Bruckert - Pediatric Drugs, 2011 - Springer
Background Early identification of children with familial hypercholesterolemia (FH) makes it
possible to start lipid-lowering therapy at a young age in order to prevent cardiovascular …
possible to start lipid-lowering therapy at a young age in order to prevent cardiovascular …
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