Recent drug design strategies and identification of key heterocyclic scaffolds for promising anticancer targets
A Mushtaq, P Wu, MM Naseer - Pharmacology & Therapeutics, 2023 - Elsevier
Cancer, a noncommunicable disease, is the leading cause of mortality worldwide and is
anticipated to rise by 75% in the next two decades, reaching approximately 25 million cases …
anticipated to rise by 75% in the next two decades, reaching approximately 25 million cases …
Heterocyclic scaffolds: centrality in anticancer drug development
I Ali, M Nadeem Lone, ZA Al-Othman… - Current drug …, 2015 - ingentaconnect.com
Cancer has been cursed for human beings for long time. Millions people lost their lives due
to cancer. Despite of the several anticancer drugs available, cancer cannot be cured; …
to cancer. Despite of the several anticancer drugs available, cancer cannot be cured; …
[图书][B] Key Heterocyclic Cores for Smart Anticancer Drug–Design Part I
RK Singh - 2022 - books.google.com
This book provides an update on heterocyclic compounds that serve as key components of
anti-cancer agents administered in pre-clinical settings. Many of the compounds highlighted …
anti-cancer agents administered in pre-clinical settings. Many of the compounds highlighted …
Deciphering the key heterocyclic scaffolds in targeting microtubules, kinases and carbonic anhydrases for cancer drug development
MN Peerzada, E Hamel, R Bai, CT Supuran… - Pharmacology & …, 2021 - Elsevier
Heterocyclic scaffolds are widely utilized for drug design by taking into account the
molecular structure of therapeutic targets that are related to a broad spectrum of ailments …
molecular structure of therapeutic targets that are related to a broad spectrum of ailments …
Heterocyclic anticancer compounds: recent advances and the paradigm shift towards the use of nanomedicine's tool box
The majority of heterocycle compounds and typically common heterocycle fragments
present in most pharmaceuticals currently marketed, alongside with their intrinsic versatility …
present in most pharmaceuticals currently marketed, alongside with their intrinsic versatility …
[PDF][PDF] The importance of heterocyclic compounds in anti-cancer drug design
S Pearce - Drug Discovery, 2017 - ddw-online.com
Heterocycles are key structural components of many of the anti-cancer drugs available on
the market today. Indeed, of the novel molecular anti-cancer agents approved by the FDA …
the market today. Indeed, of the novel molecular anti-cancer agents approved by the FDA …
Heterocyclic Molecular Targeted Drugs and Nanomedicines for Cancer: Recent Advances and Challenges
J Liu, T Chao, Y Liu, C Gong, Y Zhang, H Xiong - Pharmaceutics, 2023 - mdpi.com
Cancer is a top global public health concern. At present, molecular targeted therapy has
emerged as one of the main therapies for cancer, with high efficacy and safety. The medical …
emerged as one of the main therapies for cancer, with high efficacy and safety. The medical …
Heterocyclic Compounds: Importance in Anticancer Drug Discovery
N Kumar, N Goel - Anti-Cancer Agents in Medicinal Chemistry …, 2022 - ingentaconnect.com
Cancer, a crucial global health problem, is characterized by abnormal cell division and
uncontrolled growth. According to WHO, cancer is the second leading cause of global …
uncontrolled growth. According to WHO, cancer is the second leading cause of global …
Novel anticancer agents and targets: recent advances and future perspectives
KP Barot, S Nikolova, I Ivanov… - Mini Reviews in …, 2013 - ingentaconnect.com
An urgent need for the discovery of novel anticancer agents is required for the long term
therapy of cancer. Large number of novel bio-active and potential anticancer agents are …
therapy of cancer. Large number of novel bio-active and potential anticancer agents are …
[PDF][PDF] FDA-approved heterocyclic molecules for cancer treatment: Synthesis, dosage, mechanism of action and their adverse effect
As the incorporation of heterocycles increases the physical characteristics and biological
activity of pharmacological molecules, heterocyclic scaffolds are commonly discovered as …
activity of pharmacological molecules, heterocyclic scaffolds are commonly discovered as …