Background Circ-ITCH is a circRNA generated from several exons of itchy E3 ubiquitin
protein ligase (ITCH) and tumor suppressor served as a sponge for certain miRNAs …

Abstract Background Circular RNA Itchy E3 ubiquitin protein ligase (Circ-ITCH) is
significantly down-regulated in various kinds of tumors, however, the mechanisms of action …

Abstract Background Circular RNAs (circRNAs) are a novel class of endogenous noncoding
RNAs formed by a covalently closed loop, and increasing evidence has revealed that …

As the leading cause of death for gynecological cancers, ovarian cancer (OC) ranks fifth
overall for cancer-related death among women. Emerging evidence has indicated that …

Circular RNAs (circRNAs) are considered as a new regulatory factor in growth, metastasis
and therapeutic resistance of human cancers. But the clinical significance and underlying …

As a special form of noncoding RNAs, circular RNAs (circRNAs) played important roles in
regulating cancer progression mainly by functioning as miRNA sponge. While the function of …

Growing evidence suggests that circular RNAs (circRNAs) play pivotal roles in cancer
progression. In this study, bioinformatic analysis identified a dysregulated circRNA termed …

Background Increasing evidences indicate that circular RNAs exert critical function in
regulating bladder cancer progression. However, the expressive patterns and roles of …

Circular RNAs (circRNAs) are a new type of endogenous noncoding RNAs with closed
circular structure. Emerging evidence indicates that circRNAs play crucial roles in many …

Abstract Background Circular RNAs (circRNAs) represent a subclass of regulatory RNAs
that have been shown to have significant regulatory roles in cancer progression. However …