Importance Although tramadol is increasingly used to manage chronic noncancer pain, few
safety studies have compared it with other opioids. Objective To assess the associations of …

Abstract Purpose of Review Deaths associated to tramadol, a synthetic opioid, are rising
globally. Herein, we characterize prescription patterns of tramadol relative to other opioids in …

Importance Tramadol is a weak opioid analgesic whose use has increased rapidly, and it
has been associated with adverse events of hypoglycemia. Objective To assess whether …

Objective To determine the risk of prolonged opioid use in patients receiving tramadol
compared with other short acting opioids. Design Observational study of administrative …

Background Case reports have signaled a possible association between tramadol, a weak
opioid analgesic, and hyponatremia. The objective of this study was to determine whether …

Purpose This study aimed to develop hypotheses to explain the increasing tramadol
utilisation, evaluate the impact of tramadol classification, and explore the trend between …

Purpose To describe the use of tramadol and other analgesics in Denmark focusing on the
impact of media attention (June and December 2017) and regulatory actions (September …

Objective: To analyze the rates of misuse-that is, use in any way not directed by a doctor-of
products containing oral tramadol, a Schedule IV opioid, from the National Survey of Drug …

Tramadol is a low-level opioid increasingly recommended to treat moderate-to-severe acute
and chronic pain. Although characterized as having fewer opioid-related adverse events, the …

Methods. Records of all physicians monitored in the Alabama Physician Health Program
and the Michigan Health Professionals Recovery Program 1994-2002 were analyzed for all …