[HTML][HTML] Structural and mechanical properties of the red blood cell's cytoplasmic membrane seen through the lens of biophysics

S Himbert, MC Rheinstädter - Frontiers in Physiology, 2022 - frontiersin.org
Red blood cells (RBCs) are the most abundant cell type in the human body and critical
suppliers of oxygen. The cells are characterized by a simple structure with no internal …

[HTML][HTML] The bending rigidity of the red blood cell cytoplasmic membrane

S Himbert, A D'Alessandro, SM Qadri, MJ Majcher… - PLoS …, 2022 - journals.plos.org
An important mechanical property of cells is the membrane bending modulus, κ. In the case
of red blood cells (RBCs) there is a composite membrane consisting of a cytoplasmic …

Structural and mechanical heterogeneity of the erythrocyte membrane reveals hallmarks of membrane stability

L Picas, F Rico, M Deforet, S Scheuring - ACS nano, 2013 - ACS Publications
The erythrocyte membrane, a metabolically regulated active structure that comprises lipid
molecules, junctional complexes, and the spectrin network, enables the cell to undergo …

[HTML][HTML] Erythrocyte membrane model with explicit description of the lipid bilayer and the spectrin network

H Li, G Lykotrafitis - Biophysical journal, 2014 - cell.com
The membrane of the red blood cell (RBC) consists of spectrin tetramers connected at actin
junctional complexes, forming a two-dimensional (2D) sixfold triangular network anchored to …

Lipid bilayer and cytoskeletal interactions in a red blood cell

Z Peng, X Li, IV Pivkin, M Dao… - Proceedings of the …, 2013 - National Acad Sciences
We study the biomechanical interactions between the lipid bilayer and the cytoskeleton in a
red blood cell (RBC) by developing a general framework for mesoscopic simulations. We …

Cytoskeletal dynamics of human erythrocyte

J Li, G Lykotrafitis, M Dao… - Proceedings of the …, 2007 - National Acad Sciences
The human erythrocyte (red blood cell, RBC) demonstrates extraordinary ability to undergo
reversible large deformation and fluidity. Such mechanical response cannot be consistently …

[HTML][HTML] Blood bank storage of red blood cells increases RBC cytoplasmic membrane order and bending rigidity

S Himbert, SM Qadri, WP Sheffield, P Schubert… - PLoS …, 2021 - journals.plos.org
Blood banks around the world store blood components for several weeks ensuring its
availability for transfusion medicine. Red blood cells (RBCs) are known to undergo …

Ultrastructure and function of membrane skeleton

BW Shen - Red Blood Cell Membranes, 2020 - taylorfrancis.com
The membrane of the human erythrocyte is reinforced along its entire cytoplasmic surface by
a two-dimensional network of peripheral proteins that closely adhere to the membrane …

[HTML][HTML] The molecular structure of human red blood cell membranes from highly oriented, solid supported multi-lamellar membranes

S Himbert, RJ Alsop, M Rose, L Hertz, A Dhaliwal… - Scientific reports, 2017 - nature.com
We prepared highly oriented, multi-lamellar stacks of human red blood cell (RBC)
membranes applied on silicon wafers. RBC ghosts were prepared by hemolysis and applied …

Measurement of the nonlinear elasticity of red blood cell membranes

YK Park, CA Best, T Kuriabova, ML Henle, MS Feld… - Physical Review E …, 2011 - APS
The membranes of human red blood cells (RBCs) are a composite of a fluid lipid bilayer and
a triangular network of semiflexible filaments (spectrin). We perform cellular microrheology …