Objective.—This review of the pharmacologic treatment of heart failure due to left ventricular
systolic dysfunction summarizes the recommendations of the expert panel for the Agency for …

Over the past decade, the conceptual understanding of heart failure has changed
significantly. Several large clinical trials have demonstrated that pharmacologic …

Several large clinical trials conducted over the past decade have shown that pharmacologic
interventions can dramatically reduce the morbidity and mortality associated with heart …

Left ventricular systolic dysfunction is associated with neurohormonal activation which
contributes to progressive ventricular remodeling and worsening clinical heart failure. Renin …

In this article literature concerning the major drugs used in the treatment of heart failure is
reviewed. Because of major discrepancies in results from short term and uncontrolled …

Background Although digoxin is effective in the treatment of patients with chronic heart
failure who are receiving diuretic agents, it is not clear whether the drug has a role when …

Heart Failure: A Class Review of Pharmacotherapy - PMC Back to Top Skip to main content NIH
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Heart failure is a common and costly medical condition. Ischemic heart disease and
hypertension account for most cases of heart failure in developed countries. Estimates of the …

This document is available on the HFSA web site (www. hfsa. org). Single reprints are
available by faxing a request to 612-624-2174 or writing to HFSA, Box 358,420 Delaware …

ContextAdvanced heart failure, defined as persistence of limiting symptoms despite therapy
with agents of proven efficacy, accounts for the majority of morbidity and mortality in heart …