Nose-to-brain drug delivery: An update on clinical challenges and progress towards approval of anti-Alzheimer drugs
Abstract According to the Alzheimer Association Report (2017), Alzheimer's disease (AD) is
the 6th primary cause of death in the USA, which affects nearly 5.5 million people. In the …
the 6th primary cause of death in the USA, which affects nearly 5.5 million people. In the …
Nose-to-brain drug delivery approach: A key to easily accessing the brain for the treatment of Alzheimer's disease
A Alexander, S Saraf - Neural regeneration research, 2018 - journals.lww.com
Alzheimer's disease (AD): AD, a neurodegenerative disorder and a significant cause of
dementia throughout the world mostly affects the older adults but sometimes also seen in …
dementia throughout the world mostly affects the older adults but sometimes also seen in …
Intranasal drug delivery for treatment of Alzheimer's disease
The Alzheimer's disease is a neurodegenerative condition with severe consequences
interfering with patient quality of life. It is characterized as a progressive and irreversible …
interfering with patient quality of life. It is characterized as a progressive and irreversible …
Intranasal delivery of nanoformulations: a potential way of treatment for neurological disorders
Although the global prevalence of neurological disorders such as Parkinson's disease,
Alzheimer's disease, glioblastoma, epilepsy, and multiple sclerosis is steadily increasing …
Alzheimer's disease, glioblastoma, epilepsy, and multiple sclerosis is steadily increasing …
Intranasal therapeutic strategies for management of Alzheimer's disease
S Sood, K Jain, K Gowthamarajan - Journal of drug targeting, 2014 - Taylor & Francis
Alzheimer's disease (AD) is a chronic and progressive age-related irreversible
neurodegenerative disorder that represents 70% of all dementia with 35 million cases …
neurodegenerative disorder that represents 70% of all dementia with 35 million cases …
Nose-to-brain delivery
P Giunchedi, E Gavini, MC Bonferoni - Pharmaceutics, 2020 - mdpi.com
Nose-to-brain delivery represents a big challenge. In fact there is a large number of
neurological diseases that require therapies in which the drug must reach the brain …
neurological diseases that require therapies in which the drug must reach the brain …
Recent patents review on intranasal administration for CNS drug delivery
A Misra, V Jogani, K Jinturkar… - Recent patents on drug …, 2008 - ingentaconnect.com
The treatment of brain disorders is the greatest challenge because of a variety of formidable
obstacles in effective drug delivery and maintaining therapeutic concentrations in the brain …
obstacles in effective drug delivery and maintaining therapeutic concentrations in the brain …
Nanotechnology for enhanced nose-to-brain drug delivery in treating neurological diseases
Q Huang, Y Chen, W Zhang, X Xia, H Li, M Qin… - Journal of Controlled …, 2024 - Elsevier
Despite the increasing global incidence of brain disorders, achieving sufficient delivery
towards the central nervous system (CNS) remains a formidable challenge in terms of …
towards the central nervous system (CNS) remains a formidable challenge in terms of …
Intranasal nanotherapeutics for brain targeting and clinical studies in Parkinson's disease
Parkinson's disease (PD) is the second leading neurodegenerative disease globally,
impacting the quality of life of millions of people. It is estimated that the treatment cost of PD …
impacting the quality of life of millions of people. It is estimated that the treatment cost of PD …
Insights into direct nose to brain delivery: current status and future perspective
Now a day's intranasal (in) drug delivery is emerging as a reliable method to bypass the
blood–brain barrier (BBB) and deliver a wide range of therapeutic agents including both …
blood–brain barrier (BBB) and deliver a wide range of therapeutic agents including both …