Phosphatidylcholine biosynthesis and lipoprotein metabolism
LK Cole, JE Vance, DE Vance - … et Biophysica Acta (BBA)-Molecular and …, 2012 - Elsevier
Phosphatidylcholine (PC) is the major phospholipid component of all plasma lipoprotein
classes. PC is the only phospholipid which is currently known to be required for lipoprotein …
classes. PC is the only phospholipid which is currently known to be required for lipoprotein …
Role of phosphatidylcholine biosynthesis in the regulation of lipoprotein homeostasis
DE Vance - Current opinion in lipidology, 2008 - journals.lww.com
Role of phosphatidylcholine biosynthesis in the regulation o... : Current Opinion in Lipidology
Role of phosphatidylcholine biosynthesis in the regulation of lipoprotein homeostasis …
Role of phosphatidylcholine biosynthesis in the regulation of lipoprotein homeostasis …
The role of phosphatidylcholine biosynthesis in the secretion of lipoproteins from hepatocytes
JE Vance, DE Vance - … Journal of Biochemistry and Cell Biology, 1985 - cdnsciencepub.com
An investigation of the role of phospholipids in lipoprotein assembly and secretion is
important since phospholipids, particularly phosphatidylcholine, are prominent components …
important since phospholipids, particularly phosphatidylcholine, are prominent components …
[HTML][HTML] Hepatic CTP: phosphocholine cytidylyltransferase-α is a critical predictor of plasma high density lipoprotein and very low density lipoprotein
RL Jacobs, S Lingrell, Y Zhao, GA Francis… - Journal of biological …, 2008 - ASBMB
CTP: phosphocholine cytidylyltransferase (CT) is the key regulatory enzyme in the CDP-
choline pathway for the biosynthesis of phosphatidylcholine (PC). We previously generated …
choline pathway for the biosynthesis of phosphatidylcholine (PC). We previously generated …
[HTML][HTML] Insights into the requirement of phosphatidylcholine synthesis for liver function in mice
AA Noga, DE Vance - Journal of lipid research, 2003 - ASBMB
Phosphatidylcholine (PC) is made in the liver by the CDP-choline pathway and via
phosphatidylethanolamine N-methyltransferase (PEMT), which catalyzes the conversion of …
phosphatidylethanolamine N-methyltransferase (PEMT), which catalyzes the conversion of …
[HTML][HTML] A choline-deficient diet in mice inhibits neither the CDP-choline pathway for phosphatidylcholine synthesis in hepatocytes nor apolipoprotein B secretion
A Kulinski, DE Vance, JE Vance - Journal of Biological Chemistry, 2004 - ASBMB
Phosphatidylcholine is a major component of very low density lipoproteins (VLDLs) secreted
by the liver. Hepatic phosphatidylcholine is synthesized from choline via the CDP-choline …
by the liver. Hepatic phosphatidylcholine is synthesized from choline via the CDP-choline …
Head group specificity in the requirement of phosphatidylcholine biosynthesis for very low density lipoprotein secretion from cultured hepatocytes
We have demonstrated that hepatic very low density lipoprotein (VLDL) secretion requires
active phosphatidylcholine (PC) synthesis via either the CDP-choline pathway or …
active phosphatidylcholine (PC) synthesis via either the CDP-choline pathway or …
[HTML][HTML] The critical role of phosphatidylcholine and phosphatidylethanolamine metabolism in health and disease
JN van der Veen, JP Kennelly, S Wan, JE Vance… - … et Biophysica Acta (BBA …, 2017 - Elsevier
Phosphatidylcholine (PC) and phosphatidylethanolamine (PE) are the most abundant
phospholipids in all mammalian cell membranes. In the 1950s, Eugene Kennedy and co …
phospholipids in all mammalian cell membranes. In the 1950s, Eugene Kennedy and co …
Regulation of phosphatidylcholine biosynthesis
C Kent - Progress in lipid research, 1991 - Elsevier
Phosphatidylcholine (PC) is the major membrane phospholipid in most animals, accounting
for about half of the phospholipids in cells and over half of serum phospholipids. There are a …
for about half of the phospholipids in cells and over half of serum phospholipids. There are a …
[HTML][HTML] The membrane lipid phosphatidylcholine is an unexpected source of triacylglycerol in the liver
JN Van Der Veen, S Lingrell, DE Vance - Journal of Biological Chemistry, 2012 - ASBMB
The increased prevalence of obesity and diabetes in human populations can induce the
deposition of fat (triacylglycerol) in the liver (steatosis). The current view is that most hepatic …
deposition of fat (triacylglycerol) in the liver (steatosis). The current view is that most hepatic …